Author(s): Kristie Huda, Dylan J. Lawrence, Weylan Thompson, Sarah H. Lindsey & Carolyn L. Bayer ABSTRACT Altered vasoactivity is a major characteristic of cardiovascular and oncological diseases, and many therapies are therefore targeted to the vasculature. Therapeutics which are selective for the diseased vasculature are ideal, but whole-body selectivity of a therapeutic is challenging to assess […]
Tag: developmental biology
Investigating the Impact of Chronical Prenatal Alcohol Exposure on Fetal Vascular Development Across Pregnancy Stages Using Photoacoustic Tomography
Author(s): Hao Yang, Md Farhan Tanvir, Huabei Jiang ABSTRACT This study investigates the effects of chronic prenatal alcohol exposure on fetal brain vascular development in mice using photoacoustic tomography. Key vascular parameters such as vessel diameter, density, and oxygen saturation were analyzed from embryonic Days 10 to 20. Results demonstrate significant vascular disruptions in alcohol-exposed groups […]
FUNCTIONAL PHOTOACOUSTIC IMAGING FOR PLACENTAL MONITORING: A MINI REVIEW
Author(s): Vinoin Devpaul Vincely, Carolyn L Bayer ABSTRACT The placenta, a highly vascularized interface between the mother and fetus, undergoes dramatic anatomical and functional changes during pregnancy. These changes occur both during healthy development and adverse pathologies of pregnancy, such as preeclampsia. Abnormal placental development can lead to life-long health impacts on both the mother and […]
MONITORING NEONATAL BRAIN HEMORRHAGE PROGRESSION BY PHOTOACOUSTIC TOMOGRAPHY
Author(s): Tianqi Shan, Hao Yang, Shixie Jiang, and Huabei Jiang ABSTRACT Neonatal brain hemorrhage (NBH) is the most common neurological disorder in neonates and its clinical interventions are very limited. Understanding the pathology of NBH by non-invasive in-vivo characterization of standardized animal models is essential for developing potential treatments. Currently, there is no suitable tool […]
