Author(s): Kristie Huda , Chengxi Wu , Jaclyn G. Sider, Carolyn L. Bayer ABSTRACT Photoacoustic tomography has great potential to image dynamic functional changes in vivo. Many tomographic systems are built with a circular view geometry, necessitating a linear translation along one axis of the subject to obtain a three-dimensional volume. In this work, we evaluated a prototype […]
Tag: small animal imaging
A 3D IMAGING SYSTEM INTEGRATING PHOTOACOUSTIC AND FLUORESCENCE ORTHOGONAL PROJECTIONS FOR ANATOMICAL, FUNCTIONAL, AND MOLECULAR ASSESSMENT OF RODENT MODELS
Authors: Hans P. Brecht, Vassili Ivanov, Diego S. Dumani, Stanislav Y. Emelianov, Mark A. Anastasio, Sergey A. Ermilov ABSTRACT We have developed a preclinical 3D imaging instrument integrating photoacoustic tomography and fluorescence (PAFT) addressing known deficiencies in sensitivity and spatial resolution of the individual imaging components. PAFT is designed for simultaneous acquisition of photoacoustic and fluorescence orthogonal projections at each […]
COMMERCIAL SMALL ANIMAL IMAGING COULD AID DISEASE DETECTION
Authors: Mark Little Photoacoustic and optical images of the ventrodorsal view of a mouse specimen: 532 nm (yellow, skin level) + 890 nm (red, deep anatomy) (a); 532 nm (yellow, skin level) + 780 nm (green, ICG detecting) (b) and 532 nm (yellow, skin level) + 780 nm (green, ICG detecting) + FMT (blue, 780-nm excitation) (c). Injection site, […]
