Author(s): Nadia Abu Farha1, Parker Harris, Margaret Allard, Teodoro Trujillo, Stephen Cowen, Katalin Gothard4, Martin Weinand, Paul Larson, Ying-Hui Chou, Nan-Kuei Chen, Yeonjoon Cheong, Matthew O’Donnell6, Russell S Witte ABSTRACT Abstract not yet added. Read the full publication → Citation N. Abu Farha, P. Harris, M. Allard, T. Trujillo, S. Cowen, K. Gothard, M. Weinand, P. […]
Author: PhotoSound
Clinical Pilot Study of Ionizing Radiation Acoustic Imaging for Real-Time Visualization of Radiation Therapy Dose Delivery in Cancer Patients
Author(s): K. C. Cuneo, W. Zhang, D. Litzenberg, Y. Huang, S. Hadley, I. Oraiqat, K.-W. Chang, G. Gonzalez, S. Dykstra, M. Zhang, E. G. Moros, P. L. Carson, I. El Naqa, and X. Wang ABSTRACT This study aimed to evaluate the feasibility of using ionizing radiation acoustic imaging (iRAI) to map the delivered dose in […]
Nanosecond Pulsed Light Emitting Diode (LED) Based High-Speed Photoacoustic Computed Tomography Using Multiple Single-Element Ultrasound Transducers
Author(s): Avishek Das, Manojit Pramanik ABSTRACT Light-emitting diodes (LEDs) emerge as a viable alternative to pulsed lasers in photoacoustic computed tomography (PACT) due to their low cost, compact form factor, wavelength flexibility, and reduced safety concerns. Unlike class-IV laser systems, LED-based excitation eliminates regulatory constraints while enabling high pulse-repetition rates (PRRs) and flexible modulation for […]
Phototherapy mode control by tuning molecular and supramolecular forms of indocyanine green in crosslinked polyion complex nanoparticles
Author(s): Aixa Aguilera-Garrido, Marie Millard, Mathilde Bouché, Pascal Lemière, Nadia Canilho, Andreea Pasc, Kazunori Kataoka, Joachim F.R. Van Guyse, Henri-Pierre Lassalle, Yann Bernhard ABSTRACT Photothermal therapy (PTT) offers a minimally invasive approach for treating hypoxic tumors, while photodynamic therapy (PDT) is limited by its oxygen dependence. Indocyanine green (ICG) is a clinically approved near-infrared (NIR) […]
Quantitative photoacoustic tomography of skin vasculature predicts subcutaneous implant exposure
Author(s): A. M. Yu, X. Huang, S. M. A. Morais, J. H. Park, D. A. Zopf, S. J. Hollister, and S. Emelianov ABSTRACT Craniofacial implants are prone to skin necrosis and exposure, likely due to implant-induced stress and ischemia. However, this relationship has not been quantitatively validated. Identifying an imaging biomarker of skin vascular health […]
Dual photoacoustic/ultrasound technologies for preclinical research: current status and future trends
Author(s): M. Pérez-Liva, M. Alonso de Leciñana, M. Gutiérrez-Fernández, J. Camacho Sosa Dias, J. F. Cruza, J. Rodríguez-Pardo, I. García-Suárez, F. Laso-García, J. L. Herraiz, and L. Elvira Segura ABSTRACT Photoacoustic (PA) imaging, by integrating optical and ultrasound (US) modalities, combines high spatial resolution with deep tissue penetration, making it a transformative tool in biomedical […]
On the importance of low-frequency signals in functional and molecular photoacoustic computed tomography
Author(s): Tri Vu, Paul Klippel, Aidan J. Canning, Chenshuo Ma, Huijuan Zhang, Ludmila A. Kasatkina, Yuqi Tang, Jun Xia, Vladislav V. Verkhusha, Tuan Vo-Dinh, Yun Jing, Junjie Yao ABSTRACT In photoacoustic computed tomography (PACT) with short-pulsed laser excitation, wideband acoustic signals are generated in biological tissues with frequencies related to the effective shapes and sizes […]
Bornite (Cu5FeS4) nanocrystals as an ultrasmall biocompatible NIR-II contrast agent for photoacoustic imaging
Author(s):Vinoin Devpaul Vincely, Xingjian Zhong, Kristie Huda, Swathi P. Katakam, Joshua C. Kays, Allison M. Dennis, Carolyn L. Bayer ABSTRACT In this study, we demonstrate the potential of the bornite crystal structure (Cu5FeS4) of copper iron sulfide as a second near infrared (NIR-II) photoacoustic (PA) contrast agent. Bornite exhibits comparable dose-dependent biocompatibility to copper sulfide nanoparticles in a cell viability study with HepG2 cells, while exhibiting a 10-fold increase […]
Machine-Learning-Based Colorectal Tissue Classification via Acoustic Resolution Photoacoustic Microscopy
Author(s): Shangqing Tong, Peng Ge, Yanan Jiao, Zhaofu Ma, Ziye Li, Longhai Liu, Feng Gao, Xiaohui Du, Fei Gao ABSTRACT Colorectal cancer is a deadly disease that has become increasingly prevalent in recent years. Early detection is crucial for saving lives, but traditional diagnostic methods such as colonoscopy and biopsy have limitations. Colonoscopy cannot provide detailed information within the tissues affected by cancer, […]
Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels
Author(s): Zohar Or, Ahiad R. Levi, Yoav Hazan and Amir Rosenthal ABSTRACT he ability to rapidly locate blood vessels in patients is important in many clinical applications, e.g., in catheterization procedures. Optical techniques, including visual inspection, generally suffer from a reduced performance at depths below 1 mm, while ultrasound and optoacoustic tomography are better suited […]
