Author(s): F. Ghane Golmohamadi, A. Mehmood, H. T. Phan, F.-J. Schmitt, and J. Laufer ABSTRACT Pump-probe excitation of fluorophores has been shown to overcome the limitations of conventional multiwavelength imaging and linear unmixing approaches by providing fluorophore-specific contrast whilst eliminating the dominant background signal of endogenous chromophores. In this study, methods for generating pump-probe signals and images are […]
Author: PhotoSound
Single Wavelength Reconstruction of Optical Absorption Coefficient and Elastic Modulus Utilizing Photoacoustic Tomography
Author(s): L. Gong, C. Cai, F. Lin, Z. Xu, Z. Wang, H. Li, and Y. Liu ABSTRACT In this study, we utilized a home-made photoacoustic tomography system to recover optical absorption coefficient and elastic modulus under single wavelength. To reconstruct the optical absorption coefficient from photoacoustic measurements, we amalgamate the finite element solutions to the […]
3D Frequency-Domain Full Waveform Inversion for Whole-Breast Imaging With a Multi-Row Ring Array
Author(s): R. Ali, G. Jin, M. Singh, T. Mitcham, and N. Duric Comparison of 2D slicewise to 3D FWI with simulated multi-row ring array. Cylindrical wave transmits from a multi-row ring-array (32 rows; 256 elements per row; 22 cm diameter; 2.4 mm between rows) were simulated in three different numerical breast phantoms. Orthographic slice views […]
Enhanced clinical photoacoustic vascular imaging through a skin localization network and adaptive weighting
Author(s): Chuqin Huang, Emily Zheng, Wenhan Zheng, Huijuan Zhang, Yanda Cheng, Xiaoyu Zhang, Varun Shijo, Robert W. Bing, Isabel Komornicki, Linda M. Harris, Ermelinda Bonaccio, Kazuaki Takabe, Emma Zhang, Wenyao Xu, Jun Xia ABSTRACT Photoacoustic tomography (PAT) is an emerging imaging modality with widespread applications in both preclinical and clinical studies. Despite its promising capabilities to provide high-resolution images, the […]
Utility of Low-Cost Multichannel Data Acquisition System for Photoacoustic Computed Tomography
Author(s): Zafar, Mohsin, Rayyan Manwar, Seyed Mohsen Ranjbaran, and Kamran Avanaki ABSTRACT Typically, multi-single-element photoacoustic computed tomography (PACT) systems utilize numerous ultrasound transducers arranged in cylindrical or hemispherical configurations for detection, combined with a single diffuse light source or multiple sparse light sources to illuminate the imaging target. While these systems produce high-quality 3D PA images, […]
Signal-domain speed-of-sound correction for ring-array-based photoacoustic tomography
Author(s): Daohuai Jiang, Hengrong Lan, Shangqing Tong, Xianzeng Zhang, Fei Gao ABSTRACT Photoacoustic imaging combines the advantages of optical and acoustic imaging, making it a promising tool in biomedical imaging. Photoacoustic tomography (PAT) reconstructs images by solving the inverse problem from detected photoacoustic waves to initial pressure map. The heterogeneous speed of sound (SoS) distribution in biological tissue significantly affects […]
Advancing precision photothermal therapy byintegrating armored gold nanostars with real-timephotoacoustic thermometry and imaging
Author(s): Aidan J. Canning, Tri Vu1, Luca Menozzi, Paul Klippel, Xinrong Chen, Jianing Chen,Theresa Charity, Khang Hoang, Joseph J. Yang, Yun Jing, Gregory M. Palmer5,Junjie Yao1, Tuan Vo-Dinh ABSTRACT Nanoparticle-mediated photothermal therapy (PTT) is a promising strategy for cancer treatment; however,nanoparticle instability and lack of precise imaging tools for real-time temperature monitoring during therapyand nanoparticle tracking […]
Investigating the Impact of Chronical Prenatal Alcohol Exposure on Fetal Vascular Development Across Pregnancy Stages Using Photoacoustic Tomography
Author(s): Hao Yang, Md Farhan Tanvir, Huabei Jiang ABSTRACT This study investigates the effects of chronic prenatal alcohol exposure on fetal brain vascular development in mice using photoacoustic tomography. Key vascular parameters such as vessel diameter, density, and oxygen saturation were analyzed from embryonic Days 10 to 20. Results demonstrate significant vascular disruptions in alcohol-exposed groups […]
A comparative study of plasmonic nanoparticles for targeted photothermal therapy of melanoma tumors using various irradiation modes
Author(s): L. Mikhailova, E. Vysotina, M. Timofeeva, E. Kopoleva, V. Gulinyan, O. Pashina, K. Arabuli, O. Gusliakova, E. Prikhozhdenko, X. Qi, A. Petrov, E. Ageev, M. Petrov, C. De Angelis, M. Durymanov, G. Sukhorukov, and M. V. Zyuzin ABSTRACT Melanoma, a highly malignant and complex form of cancer, has increased in global incidence, with a […]
Rotational ultrasound and photoacoustic tomography of the human body
Author(s): Yang Zhang, Shuai Na, Jonathan J. Russin, Karteekeya Sastry, Li Lin, Junfu Zheng, Yilin Luo, Xin Tong, Yujin An, Peng Hu, Konstantin Maslov, Tze-Woei Tan, Charles Y. Liu, Lihong V. Wang ABSTRACT Imaging the human body's morphological and angiographic information is essential for diagnosing, monitoring, and treating medical conditions. Ultrasonography performs the morphological assessment of […]
