Author(s): Nadia Abu Farha1, Parker Harris, Margaret Allard, Teodoro Trujillo, Stephen Cowen, Katalin Gothard4, Martin Weinand, Paul Larson, Ying-Hui Chou, Nan-Kuei Chen, Yeonjoon Cheong, Matthew O’Donnell6, Russell S Witte ABSTRACT Abstract not yet added. Read the full publication → Citation N. Abu Farha, P. Harris, M. Allard, T. Trujillo, S. Cowen, K. Gothard, M. Weinand, P. […]
Category: Publication
High-throughput photoacoustic tomography by integrated robotics and automation
Author(s): N. Marshall, H.-P. Brecht, W. Thompson, D. Lawrence, V. Marshall, S. Toler, S. Emelianov, A. Yu, M. A. Anastasio, U. Villa, J. Maxwell, and S. Ermilov ABSTRACT We present the development of a photoacoustic tomography (PAT) imaging system with the demonstrated capability of obtaining high-throughput scans at a sustained rate of under 1 minute […]
Assessment of a Single-Element Scanning System for Enhanced Photoacoustic Imaging of Brain Hemorrhage
Author(s): Juliana Benavides Lara, Ravi Prakash, Kamran Avanaki ABSTRACT The use of photoacoustic brain imaging for hemorrhage detection holds significant clinical importance. This study focuses on the performance of sensitivity and detection capabilities of a single-element scanning system, considering the remarkable signal-to-noise ratio of photoacoustic signals generated by a single-element transducer. By employing blood vessel-like phantoms and […]
Targeted contrast agents and activatable probes for photoacoustic imaging of cancer
Author(s): Zhenxiang Zhao, Chelsea Swartchick, Jefferson Chan ABSTRACT Photoacoustic (PA) imaging has emerged as a powerful technique for the high resolution visualization of biological processes within deep tissue. Through the development and application of exogenous targeted contrast agents and activatable probes that can respond to a given cancer biomarker, researchers can image molecular events in vivo during cancer progression. […]
Carbon Nanotube Microscale Fiber Grid as an Advanced Calibration System for Multispectral Optoacoustic Imaging
Author(s): Margarita R. Chetyrkina, Julijana Cvjetinovic, Fedor S. Fedorov, Stanislav V. Perevoschikov, Ekaterina S., Prikhozhdenko,Bjørn F. Mikladal, Yuri G. Gladush, Albert G. Nasibulin,Dmitry A. Gorin ABSTRACT Optoacoustic (photoacoustic) imaging has gained tremendous attention in research and in clinical practice as a point-of-care system for noninvasive, fast, and safe tests. The first optoacoustic (OA) tomograph has […]
Hand-Held Optoacoustic System for the Localization of Mid-Depth Blood Vessels
Author(s): Zohar Or, Ahiad R. Levi, Yoav Hazan and Amir Rosenthal ABSTRACT he ability to rapidly locate blood vessels in patients is important in many clinical applications, e.g., in catheterization procedures. Optical techniques, including visual inspection, generally suffer from a reduced performance at depths below 1 mm, while ultrasound and optoacoustic tomography are better suited […]
Machine-Learning-Based Colorectal Tissue Classification via Acoustic Resolution Photoacoustic Microscopy
Author(s): Shangqing Tong, Peng Ge, Yanan Jiao, Zhaofu Ma, Ziye Li, Longhai Liu, Feng Gao, Xiaohui Du, Fei Gao ABSTRACT Colorectal cancer is a deadly disease that has become increasingly prevalent in recent years. Early detection is crucial for saving lives, but traditional diagnostic methods such as colonoscopy and biopsy have limitations. Colonoscopy cannot provide detailed information within the tissues affected by cancer, […]
Bornite (Cu5FeS4) nanocrystals as an ultrasmall biocompatible NIR-II contrast agent for photoacoustic imaging
Author(s):Vinoin Devpaul Vincely, Xingjian Zhong, Kristie Huda, Swathi P. Katakam, Joshua C. Kays, Allison M. Dennis, Carolyn L. Bayer ABSTRACT In this study, we demonstrate the potential of the bornite crystal structure (Cu5FeS4) of copper iron sulfide as a second near infrared (NIR-II) photoacoustic (PA) contrast agent. Bornite exhibits comparable dose-dependent biocompatibility to copper sulfide nanoparticles in a cell viability study with HepG2 cells, while exhibiting a 10-fold increase […]
On the importance of low-frequency signals in functional and molecular photoacoustic computed tomography
Author(s): Tri Vu, Paul Klippel, Aidan J. Canning, Chenshuo Ma, Huijuan Zhang, Ludmila A. Kasatkina, Yuqi Tang, Jun Xia, Vladislav V. Verkhusha, Tuan Vo-Dinh, Yun Jing, Junjie Yao ABSTRACT In photoacoustic computed tomography (PACT) with short-pulsed laser excitation, wideband acoustic signals are generated in biological tissues with frequencies related to the effective shapes and sizes […]
Dual photoacoustic/ultrasound technologies for preclinical research: current status and future trends
Author(s): M. Pérez-Liva, M. Alonso de Leciñana, M. Gutiérrez-Fernández, J. Camacho Sosa Dias, J. F. Cruza, J. Rodríguez-Pardo, I. García-Suárez, F. Laso-García, J. L. Herraiz, and L. Elvira Segura ABSTRACT Photoacoustic (PA) imaging, by integrating optical and ultrasound (US) modalities, combines high spatial resolution with deep tissue penetration, making it a transformative tool in biomedical […]
