Authors: Wei Zhang,1 Ibrahim Oraiqat,2 Hao Lei,3 Paul L. Carson,1,4 Issam EI Naqa,2 and Xueding Wang1,4 ABSTRACT Objective. The goal is to increase the precision of radiation delivery during radiotherapy by tracking the movements of the tumor and other surrounding normal tissues due to respiratory and other body motions. Introduction. This work presents the recent advancement of X-ray-induced radiation acoustic imaging (xRAI) […]
Author: PhotoSound
INDOCYANINE GREEN DYE BASED BIMODAL CONTRAST AGENT TESTED BY PHOTOACOUSTIC/FLUORESCENCE TOMOGRAPHY SETUP
Authors: MAKSIM D. MOKROUSOV, WEYLAN THOMPSON, SERGEY A. ERMILOV, TATIANA ABAKUMOVA, MARINA V. NOVOSELOVA, OLGA A. INOZEMTSEVA, TIMOFEI S. ZATSEPIN, VLADIMIR P. ZHAROV, EKATERINA I. GALANZHA, DMITRY A. GORIN Visualization 1. 3D image of the samples reconstructed from the obtained photoacoustic and fluorescent measurement data ABSTRACT Multimodal imaging systems are in high demand for preclinical […]
GOLD NANOPARTICLES CONJUGATED WITH DNA APTAMER FOR PHOTOACOUSTIC DETECTION OF HUMAN MATRIX METALLOPROTEINASE-9
Authors: Jinhwan Kim, Anthony M Yu, Kelsey P. Kubelick, Stanislav Y. Emelianov Fig. 5. Spectroscopic analysis and PAT of the MMP sensor in an in vivo mouse model of breast cancer. (a) PA intensity from 680 nm to 970 nm of the MMP sensor in the tumor region and assorted controls – saline only and control sensor. Black dashed line […]
BREAKTHROUGH INSTRUMENTS AND PRODUCTS PHOTOSONUS M+ LASER FOR PHOTOACOUSTIC IMAGING
Authors: Aldas Juronis and Mantvydas Jašinskas Fig 2. A small animal whole body in vivo imaging platform TriTom based on photoacoustic fluorescence tomography with an integrated PhotoSonus M laser system. Courtesy of PhotoSound Technologies, Inc. ABSTRACT This report highlights PhotoSonus M+, a tunable wavelength laser system recently introduced and developed specifically for photoacoustic imaging applications, where the highest imaging depth and […]
PHOTOACOUSTIC TOMOGRAPHY TO ASSESSACUTE VASOACTIVITY OF SYSTEMIC VASCULATURE
Author(s): Huda, Kristieª; Lawrence, Dylanª; Lindsey, Sarah; Bayer, Carolynª* ABSTRACT Vasoactivity is an important physiological indicator of cardiovascular health which is frequently measured using ex vivo vessels to determine functional mechanisms and evaluate pharmacological responses. Currently, there are no imaging methods available to assess vasoactivity in multiple vascular beds of living animals noninvasively. In this […]
PHOTOACOUSTIC IMAGING FOR IN VIVO QUANTIFICATION OF ALCOHOL-INDUCED STRUCTURAL AND FUNCTIONAL CHANGES IN CEREBRAL VASCULATURE IN HIGH ALCOHOL-PREFERRING MICE (HAP)
Authors: Augustine Meombe Mbolle, Hao Yang, Huabei Jiang* ABSTRACT Alcohol-induced structural and functional changes were studied in vivo by photoacoustic tomography (PAT) of the cerebrovascular system in selectively bred alcohol-preferring mice. High (HAP) and low (LAP) alcohol-preferring mice are replicate lines of mice selectively bred to prefer 10% (v/v) ethanol to water and water to […]
TRANSFONTANELLE PHOTOACOUSTIC IMAGING: ULTRASOUND TRANSDUCER SELECTION ANALYSIS
Authors: Rayyan Manwar, Tarikul Islam, MD, Seyed Mohsen Ranjbaran, Kamran Avanaki ABSTRACT Transfontanelle ultrasound imaging (TFUI) is the conventional approach for diagnosing brain injury in neonates. Despite being the first stage imaging modality, TFUI lacks accuracy in determining the injury at an early stage due to degraded sensitivity and specificity. Therefore, a modality like photoacoustic […]
IN SITU X-RAY-INDUCED ACOUSTIC COMPUTED TOMOGRAPHY WITH A CONTRAST AGENT: A PROOF OF CONCEPT
Authors: Seongwook Choi,1; Sinyoung Park,1; Ayoung Pyo,2; Dong-Yeon Kim,3 ; Jung-Joon Min,4 ; Changho Lee,4,5,6; Chulhong Kim,1,7 ABSTRACT X-ray-induced acoustic computed tomography (XACT) has shown great potential as a hybrid imaging modality for real-time non-invasive x-ray dosimetry and low-dose three- dimensional (3D) imaging. While promising, one drawback of the XACT system is the underlying low signal-to-noise ratio […]
SIZE-ADJUSTABLE RING-SHAPE PHOTOACOUSTIC TOMOGRAPHY IMAGER IN VIVO
Author(s): Daohuai Jiang1,2,3, Yifei Xu1, Hengrong Lan1,2,3, Yuting Shen1, Yifan Zhang1,Feng Gao1, Li Liu4*, Fei Gao1,5* ABSTRACT Photoacoustic tomography (PAT) has become a novel biomedical imaging modality for scientific research and clinical diagnosis. It combines the advantages of spectroscopic optical absorption contrast and acoustic resolution with deep penetration. In this article, an imaging size-adjustable PAT […]
NON-INVASIVE PHOTOACOUSTIC COMPUTED TOMOGRAPHY OF RAT HEART ANATOMY AND FUNCTION
Author(s): Li Lin, Xin Tong, Susana Cavallero, Yide Zhang, Shuai Na, Rui Cao, Tzung K. Hsiai, and Lihong V. Wang ABSTRACT Photoacoustic computed tomography (PACT) combines optical contrast with acoustic-resolution imaging, but non-invasive cardiac imaging with this technique has been limited by signal loss and distortion caused by the chest wall. This work presents a […]
