Category: Publication

CHARACTERIZING A PHOTOACOUSTIC AND FLUORESCENCE IMAGING PLATFORM FOR PRECLINICAL MURINE LONGITUDINAL STUDIES

Author(s): Weylan R. Thompson, Hans-Peter F. Brecht, Vassili Ivanov, Anthony M. Yu, Diego S. Dumani, Dylan J. Lawrence, Stanislav Y. Emelianov, Sergey A. Ermilov PAT volumes and slices of in vivo mouse scans. The top PAT row shows 3D renders of the PAT volumes scanned at wavelengths (a) 532 nm for superficial structures, (b) 710 nm for deep structures with deoxygenated […]

BIODEGRADABLE AND BIOCOMPATIBLE SEMICONDUCTOR NANOCRYSTALS AS NIR-II PHOTOACOUSTIC IMAGING CONTRAST AGENTS

Author(s): Vinoin Devpaul Vincely, Swathi P. Katakam, Kristie Huda, Xingjian Zhong, Joshua C. Kays, Allison M. Dennis, Carolyn L. Bayer ABSTRACT Transabdominal imaging using photoacoustics (PA) is limited by optical attenuation of tissue due to high scattering and absorption in the near infrared (NIR) window. Tissue attenuation is lowered when imaging with longer wavelengths in the NIR window (> 950 nm). […]

IMPROVING PHOTOACOUSTIC IMAGING IN LOW SIGNAL-TO-NOISE RATIO BY USING SPATIAL AND POLARITY COHERENCE

Author(s): Qiuqin Mao, Weiwei Zhao, Xiaoqin Qian, Chao Tao, Xiaojun Liu Fig. 6. The variation curve of (a) the FWHM and (b) the image contrast with the decreased SNR of raw signals. ABSTRACT To suppress the noise and sidelobe of photoacoustic images, a method is proposed combined with spatial coherence and polarity coherence. In this method, PA signals are delayed, multiplied, then performed polarity coherence, and […]

DEEP LEARNING ENABLED REAL-TIME PHOTOACOUSTIC TOMOGRAPHY SYSTEM VIA SINGLE DATA ACQUISITION CHANNEL

Author(s): Hengrong Lan, Daohuai Jiang, Feng Gao, Fei Gao Fig. 1. The overview of the proposed single-channel PACT system. PC: personal computer. Pre-amp: Pre-amplifier. ABSTRACT Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements ultrasound array only using a single data […]

Y-NET: HYBRID DEEP LEARNING IMAGE RECONSTRUCTION FOR PHOTOACOUSTIC TOMOGRAPHY IN VIVO

Author(s): Hengrong Lan, Daohuai Jiang, Changchun Yang, Feng Gao, Fei Gao Fig. 5. The example of performance comparison using different methods to reconstruct initial pressure. The four examples correspond to four rows; every column corresponds to different method, from left to right: ground-truth, DAS, TR, Y-Net-EIID, Y-Net-EID, post-processing U-Net and Y-Net. DAS: delay-and-sum; TR: time reversal. The white circles indicate the local details. ABSTRACT Conventional reconstruction […]

RADIATION-INDUCED ACOUSTIC SIGNAL DENOISING USING A SUPERVISED DEEP LEARNING FRAMEWORK FOR IMAGING AND THERAPY MONITORING

Author(s): Zhuoran Jiang, Siqi Wang, Yifei Xu, Leshan Sun, Gilberto Gonzalez, Yong Chen, Q. Jackie Wu, Liangzhong Xiang, Lei Ren​ ABSTRACT Radiation-induced acoustic (RA) imaging is a promising technique for visualizing radiation energy deposition in tissues, enabling new imaging modalities and real-time therapy monitoring. However, it requires measuring hundreds or even thousands of averages to achieve satisfactory signal-to-noise ratios (SNRs). This repetitive […]

AUTOMATIC FORCE-CONTROLLED 3D PHOTOACOUSTIC SYSTEM FOR HUMAN PERIPHERAL VASCULAR IMAGING

Author(s): David C. Garrett, Jinhua Xu, Geng Ku, and Lihong V. Wang Fig. 1. The composition of the system. (A) The system schematics. (B) The photograph of the experiment. PA: photoacoustic; US: ultrasound ABSTRACT We developed a system for whole-body human ultrasound tomography in reflection and transmission modes. A custom 512-element ultrasound receiver array with a […]

DUAL-SCAN PHOTOACOUSTIC TOMOGRAPHY FOR THE IMAGING OF VASCULAR STRUCTURE ON FOOT

Author(s): Chuqin Huang, Yanda Cheng, Wenhan Zheng, Robert W Bing, Huijuan Zhang, Isabel Komornicki, Linda M Harris, Praveen R Arany, Saptarshi Chakraborty, Qifa Zhou, Wenyao Xu, Jun Xia ABSTRACT Chronic leg ulcers are affecting approximately 6.5 million Americans, and they are associated with significant mortality, reduced quality of life, and high treatment costs. Since many […]

EVALUATION OF ULTRASOUND SENSORS FOR TRANSCRANIAL PHOTOACOUSTIC SENSING AND IMAGING

Author(s): Thomas Kirchner, Claus Villringer, and Jan Laufer Video S1. Acoustic propagation through frontal cranial bone in silico. A 3D k-Wave forward simulation of a flat acoustic source with 5 mm diameter. Time series of the pressure distribution in the center slice. The light gray area shows the skull segmentation used for the simulation. ABSTRACT Significance: Biomedical […]

HIGH-SPEED THREE-DIMENSIONAL PHOTOACOUSTIC COMPUTED TOMOGRAPHY FOR PRECLINICAL RESEARCH AND CLINICAL TRANSLATION

Authors: Li Lin, Peng Hu, Xin Tong, Rui Cao, Xiaoyun Yuan, David C. Garrett, Junhui Shi, Konstantin Maslov & Lihong V. Wang ABSTRACT Photoacoustic computed tomography (PACT) has generated increasing interest for uses in preclinical research and clinical translation. However, the imaging depth, speed, and quality of existing PACT systems have previously limited the potential […]