Tag: animal imaging

A 3D IMAGING SYSTEM INTEGRATING PHOTOACOUSTIC AND FLUORESCENCE ORTHOGONAL PROJECTIONS FOR ANATOMICAL, FUNCTIONAL, AND MOLECULAR ASSESSMENT OF RODENT MODELS

16 March 2018 Authors: Hans P. Brecht, Vassili Ivanov, Diego S. Dumani, Stanislav Y. Emelianov, Mark A. Anastasio, Sergey A. Ermilov ABSTRACT We have developed a preclinical 3D imaging instrument integrating photoacoustic tomography and fluorescence (PAFT) addressing known deficiencies in sensitivity and spatial resolution of the individual imaging components. PAFT is designed for simultaneous acquisition of photoacoustic and fluorescence orthogonal […]

Disease Monitoring

How does PhotoSound equipment aid with disease monitoring? PhotoSound imaging equipment has been developed to aid in the research of disease progression, using their abilities to generate highly sensitive and high-resolution anatomical images whether due to structural changes from Alcohol Use Disorder, monitoring vasoconstriction during hypothermia, or imaging neovascular formation in cancer, including liver and […]

CO-REGISTERED PHOTOACOUSTIC AND FLUORESCENT IMAGING OF A SWITCHABLE NANOPROBE BASED ON J-AGGREGATES OF INDOCYANINE GREEN

Authors: Diego S. Dumani1,2, Hans-Peter Brecht3, Vassili Ivanov3, Ryan Deschner4, Justin T. Harris4, Kimberly A. Homan4, Jason R. Cook5, Stanislav Y. Emelianov1,2, Sergey A. Ermilov3 ABSTRACT We introduce a preclinical imaging platform – a 3D photoacoustic/fluorescence tomography (PAFT) instrument augmented with an environmentally responsive dual-contrast biocompatible nanoprobe. The PAFT instrument was designed for simultaneous acquisition […]