Author(s): Prabodh K Pandey, Gilberto Gonzalez, Kristina Bjegovic, Leshan Sun, Yong Chen, Liangzhong Xiang ABSTRACT We propose protoacoustic radiography (PAR), an imaging modality combining proton excitation and acoustic detection for three-dimensional (3D) imaging from a single proton projection. PAR avoids the effect of multiple Coulomb scattering in imaging by detecting ultrasound. Proton-induced acoustic waves propagate spherically, […]
Tag: Legion ADC
4D IN VIVO DOSIMETRY FOR A FLASH ELECTRON BEAM USING RADIATION-INDUCED ACOUSTIC IMAGING
Authors: Kristina Bjegovic, Leshan Sun, Prabodh Pandey, Veljko Grilj, Paola Ballesteros-Zebadua, Ryan Paisley, Gilberto Gonzalez, Siqi Wang, Marie Catherine Vozenin, Charles L Limoli and Shawn (Liangzhong) Xiang ABSTRACT Objective. The primary goal of this research is to demonstrate the feasibility of radiation-induced acoustic imaging (RAI) as a volumetric dosimetry tool for ultra-high dose rate FLASH […]
TOWARD REAL-TIME, VOLUMETRIC DOSIMETRY FOR FLASH-CAPABLE CLINICAL SYNCHROCYCLOTRONS USING PROTOACOUSTIC IMAGING
Authors: Siqi Wang, Gilberto Gonzalez, Daniel Rocky Owen, Leshan Sun, Yan Liu, Townsend Zwart, Yong Chen, Liangzhong Xiang ABSTRACT BackgroundRadiation delivery with ultra-high dose rate (FLASH) radiotherapy (RT) holds promise for improving treatment outcomes and reducing side effects but poses challenges in radiation delivery accuracy due to its ultra-high dose rates. This necessitates the development […]
REAL-TIME TRACKING OF THE BRAGG PEAK DURING PROTON THERAPY VIA 3D PROTOACOUSTIC IMAGING IN A CLINICAL SCENARIO
Authors: Siqi Wang, Gilberto Gonzalez, Leshan Sun, Yifei Xu, Prabodh Pandey, Yong Chen & Shawn (Liangzhong) Xiang ABSTRACT Proton radiotherapy favored over X-ray photon therapy due to its reduced radiation exposure to surrounding healthy tissues, is highly dependent on the accurate positioning of the Bragg peak. Existing methods like PET and prompt gamma imaging to […]
SCIENTIFIC PRESENTATIONS USING PHOTOSOUND PRODUCTS AT SPIE 2024
We look forward to seeing you at one of the scientific presentations using PhotoSound Technologies, Inc. products during SPIE Photonics West 2024. See the list of presentations below. 12842-15 The new development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy Author(s): Wei Zhang, Dale Litzenberg, […]
Model-Based 3-D X-Ray Induced Acoustic Computerized Tomography
Authors: Prabodh Kumar Pandey; Siqi Wang; Leshan Sun; Lei Xing; Liangzhong Xiang ABSTRACT X-ray-induced acoustic (XA) computerized tomography (XACT) is an evolving imaging technique that aims to reconstruct the X-ray energy deposition from XA measurements. Main challenges in XACT are the poor signal-to-noise ratio and limited field-of-view, which cause artifacts in the images. We demonstrate the efficacy of model-based […]
Discrete Wavelet Transformation for the Sensitive Detection of Ultrashort Radiation Pulse with Radiation-Induced Acoustics
Authors: Rick Van Bergen, Leshan Sun, Prabodh Kumar Pandey, Siqi Wang, Kristina Bjegovic, Gilberto Gonzalez, Yong Chen, Richard Lopata, Liangzhong Xiang ABSTRACT Radiation-induced acoustics (RIA) shows promise in advancing radiological imaging and radiotherapy dosimetry methods. However, RIA signals often require extensive averaging to achieve reasonable signal-to-noise ratios, which increases patient radiation exposure and limits real-time […]
MONODISPERSE SUB-100 NM AU NANOSHELLS FOR LOW-FLUENCE DEEP-TISSUE PHOTOACOUSTIC IMAGING
Author(s): Luis D. B. Manuel, Vinion Devpaul Vincely, Carolyn Bayer, and Kevin M. McPeak ABSTRACT Nanoparticles with high absorption cross sections will advance therapeutic and bioimaging nanomedicine technologies. While Au nanoshells have shown great promise in nanomedicine, state-of-the-art synthesis methods result in scattering-dominant particles, mitigating their efficacy in absorption-based techniques that leverage the photothermal effect, […]
NON-INVASIVE 3D PHOTOACOUSTIC TOMOGRAPHY OF ANGIOGRAPHIC ANATOMY AND HEMODYNAMICS OF FATTY LIVERS IN RATS
Author(s): Xin Tong, Li Lin, Peng Hu, Rui Cao, Yang Zhang, Joshua Olick-Gibson,and Lihong V. Wang ABSTRACT Non-alcoholic fatty liver disease is the most common liver disorder worldwide, which strongly correlates to obesity, diabetes, and metabolic syndromes. Complementary to mainstream liver diagnostic modalities, photoacoustic tomography (PAT) can provide high-speed images with functional optical contrast. However, […]
FIBER TIP TRACKING WITH PHOTOACOUSTIC IMAGING BY USING LEGION AMP
Overview: The Legion AMP webinar series is hosted by PhotoSound Technologies Marketing Specialist’s Sarah Argo. In the second webinar of the Legion Amp Webinar Series, Samuel Toler (System Test Engineer I), discussed the Legion Amp design, motivation, and benefits in relation to how it could optimize your research. Samuel John and Dr. Yan Yan, from […]
