Author(s): Zohar Or, Ahiad R. Levi, Yoav Hazan and Amir Rosenthal ABSTRACT he ability to rapidly locate blood vessels in patients is important in many clinical applications, e.g., in catheterization procedures. Optical techniques, including visual inspection, generally suffer from a reduced performance at depths below 1 mm, while ultrasound and optoacoustic tomography are better suited […]
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Radiomics-driven perfusion prediction in clinical photoacoustic foot imaging
Author(s): Chuqin Huang a, Yanda Cheng a, Xiaoyu Zhang b, Ye Zhan c, Wenhan Zheng a, Isabel Komornicki d, Linda M. Harris d, Wenyao Xu b, Jun Xia a ABSTRACT Accurate assessment of tissue perfusion is essential for managing chronic foot ulcers in patients with diabetes and peripheral arterial disease. While photoacoustic (PA) imaging enables high-resolution […]
Investigating the Impact of Prenatal Alcohol Exposure on Fetal Cardiac Development Using Photoacoustic Tomography
Author(s): M. F. Tanvir, H. Yang, J. D. Gardner, and H. Jiang ABSTRACT Prenatal alcohol exposure (PAE) is a leading cause of developmental abnormalities, yet its effects on fetal cardiac development remain understudied. We employed real-time, label-freemultispectral photoacoustic tomography (PAT) to noninvasively assess cardiac development in mouse fetuses exposed to chronic alcohol. Using a custom-built […]
Direct Monitoring of Whole-Brain Electrodynamics via High-Spatiotemporal-Resolution Photoacoustics with Voltage-Sensitive Dye
Author(s): W. Pang, B. Zhu, H. Li, Y. Zhou, C. M. Woo, X. Huang, T. Zhong, H. Lo, L. Wang, P. Lai, and L. Nie ABSTRACT This work proposes a novel method for monitoring deep-brain electrodynamics with a voltage-sensitive dye (VSD)-based photoacoustic imaging platform, called PA-VSD. This platform is demonstrated to allow for effectively localizing […]
Single Wavelength Reconstruction of Optical Absorption Coefficient and Elastic Modulus Utilizing Photoacoustic Tomography
Author(s): L. Gong, C. Cai, F. Lin, Z. Xu, Z. Wang, H. Li, and Y. Liu ABSTRACT In this study, we utilized a home-made photoacoustic tomography system to recover optical absorption coefficient and elastic modulus under single wavelength. To reconstruct the optical absorption coefficient from photoacoustic measurements, we amalgamate the finite element solutions to the […]
3D Frequency-Domain Full Waveform Inversion for Whole-Breast Imaging With a Multi-Row Ring Array
Author(s): R. Ali, G. Jin, M. Singh, T. Mitcham, and N. Duric Comparison of 2D slicewise to 3D FWI with simulated multi-row ring array. Cylindrical wave transmits from a multi-row ring-array (32 rows; 256 elements per row; 22 cm diameter; 2.4 mm between rows) were simulated in three different numerical breast phantoms. Orthographic slice views […]
Enhanced clinical photoacoustic vascular imaging through a skin localization network and adaptive weighting
Author(s): Chuqin Huang, Emily Zheng, Wenhan Zheng, Huijuan Zhang, Yanda Cheng, Xiaoyu Zhang, Varun Shijo, Robert W. Bing, Isabel Komornicki, Linda M. Harris, Ermelinda Bonaccio, Kazuaki Takabe, Emma Zhang, Wenyao Xu, Jun Xia ABSTRACT Photoacoustic tomography (PAT) is an emerging imaging modality with widespread applications in both preclinical and clinical studies. Despite its promising capabilities to provide high-resolution images, the […]
Signal-domain speed-of-sound correction for ring-array-based photoacoustic tomography
Author(s): Daohuai Jiang, Hengrong Lan, Shangqing Tong, Xianzeng Zhang, Fei Gao ABSTRACT Photoacoustic imaging combines the advantages of optical and acoustic imaging, making it a promising tool in biomedical imaging. Photoacoustic tomography (PAT) reconstructs images by solving the inverse problem from detected photoacoustic waves to initial pressure map. The heterogeneous speed of sound (SoS) distribution in biological tissue significantly affects […]
Investigating the Impact of Chronical Prenatal Alcohol Exposure on Fetal Vascular Development Across Pregnancy Stages Using Photoacoustic Tomography
Author(s): Hao Yang, Md Farhan Tanvir, Huabei Jiang ABSTRACT This study investigates the effects of chronic prenatal alcohol exposure on fetal brain vascular development in mice using photoacoustic tomography. Key vascular parameters such as vessel diameter, density, and oxygen saturation were analyzed from embryonic Days 10 to 20. Results demonstrate significant vascular disruptions in alcohol-exposed groups […]
Rotational ultrasound and photoacoustic tomography of the human body
Author(s): Yang Zhang, Shuai Na, Jonathan J. Russin, Karteekeya Sastry, Li Lin, Junfu Zheng, Yilin Luo, Xin Tong, Yujin An, Peng Hu, Konstantin Maslov, Tze-Woei Tan, Charles Y. Liu, Lihong V. Wang ABSTRACT Imaging the human body's morphological and angiographic information is essential for diagnosing, monitoring, and treating medical conditions. Ultrasonography performs the morphological assessment of […]
