Direct Monitoring of Whole-Brain Electrodynamics via High-Spatiotemporal-Resolution Photoacoustics with Voltage-Sensitive Dye

Author(s): W. Pang, B. Zhu, H. Li, Y. Zhou, C. M. Woo, X. Huang, T. Zhong, H. Lo, L. Wang, P. Lai, and L. Nie


ABSTRACT

This work proposes a novel method for monitoring deep-brain electrodynamics with a voltage-sensitive dye (VSD)-based photoacoustic imaging platform, called PA-VSD. This platform is demonstrated to allow for effectively localizing epileptic foci and visualizing voltage conduction pathways in a high spatiotemporal resolution.

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Citation

W. Pang, B. Zhu, H. Li, Y. Zhou, C. M. Woo, X. Huang, T. Zhong, H. Lo, L. Wang, P. Lai, and L. Nie, "Direct Monitoring of Whole-Brain Electrodynamics via High-Spatiotemporal-Resolution Photoacoustics with Voltage-Sensitive Dye," Laser & Photonics Reviews, vol. 18, no. 10, art. 2400165, 2024, doi: 10.1002/lpor.202400165.