Tag: in vivo

Toward in vivo dosimetry in external beam radiotherapy using x-ray acoustic computed tomography: A soft-tissue phantom study validation

Author(s): Hao Lei, Wei Zhang, Ibrahim Oraiqat, Zhipeng Liu, Jun Ni, Xueding Wang, Issam El Naqa Abstract Purpose: To study, using phantoms made from biological tissues, the feasibility and practical challenges of monitoring the position of the radiation beam and the deposited dose by x-ray acoustic computed tomography (XACT) during external beam radiotherapy delivery. Material and methods: A prototype XACT system […]

SIZE-TUNABLE ICG-BASED CONTRAST AGENT PLATFORM FOR TARGETED NEAR-INFRARED PHOTOACOUSTIC IMAGING

2022 Dec 11 Author(s): Shrishti Singh, Giovanni Giammanco, Chih-Hsiang Hu, Joshua Bush, Leandro Soto Cordova, Dylan J Lawrence, Jeffrey L Moran, Parag V Chitnis, Remi Veneziano ABSTRACT Near-infrared photoacoustic imaging (NIR-PAI) combines the advantages of optical and ultrasound imaging to provide anatomical and functional information of tissues with high resolution. Although NIR-PAI is promising, its widespread use is hindered by […]

SPHERICAL-VIEW PHOTOACOUSTIC TOMOGRAPHY FOR MONITORING IN VIVO PLACENTAL FUNCTION

29 September 2020 Author(s): Kristie Huda , Chengxi Wu , Jaclyn G. Sider, Carolyn L. Bayer ABSTRACT Photoacoustic tomography has great potential to image dynamic functional changes in vivo. Many tomographic systems are built with a circular view geometry, necessitating a linear translation along one axis of the subject to obtain a three-dimensional volume. In this work, we […]

NON-INVASIVE 3D PHOTOACOUSTIC TOMOGRAPHY OF ANGIOGRAPHIC ANATOMY AND HEMODYNAMICS OF FATTY LIVERS IN RATS

17 November 2022 Author(s): Xin Tong, Li Lin, Peng Hu, Rui Cao, Yang Zhang, Joshua Olick-Gibson,and Lihong V. Wang ABSTRACT Non-alcoholic fatty liver disease is the most common liver disorder worldwide, which strongly correlates to obesity, diabetes, and metabolic syndromes. Complementary to mainstream liver diagnostic modalities, photoacoustic tomography (PAT) can provide high-speed images with functional […]

A 3D IMAGING SYSTEM INTEGRATING PHOTOACOUSTIC AND FLUORESCENCE ORTHOGONAL PROJECTIONS FOR ANATOMICAL, FUNCTIONAL, AND MOLECULAR ASSESSMENT OF RODENT MODELS

16 March 2018 Authors: Hans P. Brecht, Vassili Ivanov, Diego S. Dumani, Stanislav Y. Emelianov, Mark A. Anastasio, Sergey A. Ermilov ABSTRACT We have developed a preclinical 3D imaging instrument integrating photoacoustic tomography and fluorescence (PAFT) addressing known deficiencies in sensitivity and spatial resolution of the individual imaging components. PAFT is designed for simultaneous acquisition of photoacoustic and fluorescence orthogonal […]