Author(s): Juliana Benavides Lara, Ravi Prakash, Kamran Avanaki ABSTRACT The use of photoacoustic brain imaging for hemorrhage detection holds significant clinical importance. This study focuses on the performance of sensitivity and detection capabilities of a single-element scanning system, considering the remarkable signal-to-noise ratio of photoacoustic signals generated by a single-element transducer. By employing blood vessel-like phantoms and […]
Tag: neuroimaging
Transcranial acoustoelectric imaging (tABI) of seizure activity in human head model with neuronavigation
Author(s): Nadia Abu Farha1, Parker Harris, Margaret Allard, Teodoro Trujillo, Stephen Cowen, Katalin Gothard4, Martin Weinand, Paul Larson, Ying-Hui Chou, Nan-Kuei Chen, Yeonjoon Cheong, Matthew O’Donnell6, Russell S Witte ABSTRACT Abstract not yet added. Read the full publication → Citation N. Abu Farha, P. Harris, M. Allard, T. Trujillo, S. Cowen, K. Gothard, M. Weinand, P. […]
Direct Monitoring of Whole-Brain Electrodynamics via High-Spatiotemporal-Resolution Photoacoustics with Voltage-Sensitive Dye
Author(s): W. Pang, B. Zhu, H. Li, Y. Zhou, C. M. Woo, X. Huang, T. Zhong, H. Lo, L. Wang, P. Lai, and L. Nie ABSTRACT This work proposes a novel method for monitoring deep-brain electrodynamics with a voltage-sensitive dye (VSD)-based photoacoustic imaging platform, called PA-VSD. This platform is demonstrated to allow for effectively localizing […]
HYBRID PHOTOACOUSTIC ULTRASOUND IMAGING SYSTEM FOR COLD-INDUCED VASOCONSTRICTION AND VASODILATION MONITORING
Author(s): Ruochong Zhang, Xiuting Li, Ghayathri Balasundaram, Baocheng Li, Yi Qi, Anindita Santosa, Tze Chin Tan, Malini Olivo, Renzhe Bi ABSTRACT Lewis hunting reaction refers to the alternating cold-induced vasoconstriction and dilation in extremities, whose underlying mechanism is complex. While numerous studies reported this intriguing phenomenon by measuring cutaneous temperature fluctuation under cold exposure, few of them tracked peripheral vascular responses in real-time, […]
PHOTOACOUSTIC IMAGING FOR IN VIVO QUANTIFICATION OF ALCOHOL-INDUCED STRUCTURAL AND FUNCTIONAL CHANGES IN CEREBRAL VASCULATURE IN HIGH ALCOHOL-PREFERRING MICE (HAP)
Authors: Augustine Meombe Mbolle, Hao Yang, Huabei Jiang* ABSTRACT Alcohol-induced structural and functional changes were studied in vivo by photoacoustic tomography (PAT) of the cerebrovascular system in selectively bred alcohol-preferring mice. High (HAP) and low (LAP) alcohol-preferring mice are replicate lines of mice selectively bred to prefer 10% (v/v) ethanol to water and water to […]
TRANSFONTANELLE PHOTOACOUSTIC IMAGING: ULTRASOUND TRANSDUCER SELECTION ANALYSIS
Authors: Rayyan Manwar, Tarikul Islam, MD, Seyed Mohsen Ranjbaran, Kamran Avanaki ABSTRACT Transfontanelle ultrasound imaging (TFUI) is the conventional approach for diagnosing brain injury in neonates. Despite being the first stage imaging modality, TFUI lacks accuracy in determining the injury at an early stage due to degraded sensitivity and specificity. Therefore, a modality like photoacoustic […]
EVALUATION OF ULTRASOUND SENSORS FOR TRANSCRANIAL PHOTOACOUSTIC SENSING AND IMAGING
Author(s): Thomas Kirchner, Claus Villringer, and Jan Laufer Video S1. Acoustic propagation through frontal cranial bone in silico. A 3D k-Wave forward simulation of a flat acoustic source with 5 mm diameter. Time series of the pressure distribution in the center slice. The light gray area shows the skull segmentation used for the simulation. ABSTRACT Significance: Biomedical […]
HIGH-SPEED THREE-DIMENSIONAL PHOTOACOUSTIC COMPUTED TOMOGRAPHY FOR PRECLINICAL RESEARCH AND CLINICAL TRANSLATION
Authors: Li Lin, Peng Hu, Xin Tong, Rui Cao, Xiaoyun Yuan, David C. Garrett, Junhui Shi, Konstantin Maslov & Lihong V. Wang ABSTRACT Photoacoustic computed tomography (PACT) has generated increasing interest for uses in preclinical research and clinical translation. However, the imaging depth, speed, and quality of existing PACT systems have previously limited the potential […]
