Tag: Photoacoustic Imaging

Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy

Author(s): Iaroslav B. Belyaev, Ivan V. Zelepukin, Polina A. Kotelnikova, Gleb V. Tikhonowski, Anton A. Popov, Alina Yu. Kapitannikova, Jugal Barman, Alexey N. Kopylov, Daniil N. Bratashov, Ekaterina S. Prikhozhdenko, Andrei V. Kabashin, Sergey M. Deyev, Andrei V. Zvyagin Abstract Biodegradable nanomaterials can significantly improve the safety profile of nanomedicine. Germanium nanoparticles (Ge NPs) with a safe biodegradation pathway are developed as efficient photothermal converters for biomedical […]

Toward in vivo dosimetry in external beam radiotherapy using x-ray acoustic computed tomography: A soft-tissue phantom study validation

Author(s): Hao Lei, Wei Zhang, Ibrahim Oraiqat, Zhipeng Liu, Jun Ni, Xueding Wang, Issam El Naqa Abstract Purpose: To study, using phantoms made from biological tissues, the feasibility and practical challenges of monitoring the position of the radiation beam and the deposited dose by x-ray acoustic computed tomography (XACT) during external beam radiotherapy delivery. Material and methods: A prototype XACT system […]

Spatiotemporal Image Reconstruction to Enable High-Frame-Rate Dynamic Photoacoustic Tomography with Rotating-Gantry Volumetric Imagers

Author(s): Refik Mert Cam, Chao Wang, Weylan Thompson, Sergey A. Ermilov, Mark A. Anastasio, Umberto Villa ABSTRACT Significance Dynamic photoacoustic computed tomography (PACT) is a valuable imaging technique for monitoring physiological processes. However, current dynamic PACT imaging techniques are often limited to two-dimensional spatial imaging. Although volumetric PACT imagers are commercially available, these systems typically employ a rotating measurement gantry […]

Water-Soluble Fe(II) Complexes for Theranostic Application: Synthesis, Photoacoustic Imaging, and Photothermal Conversion

Authors: Maeva Delcroix, Dr. Anil Reddy Marri, Stéphane Parant, Dr. Philippe C. Gros, Dr. Mathilde Bouché ABSTRACT Significant effort focused on developing photoactivatable theranostics for localized image guided therapy of cancer by thermal ablation. In this context iron complexes were recently identified as photoactivatable theranostic agents with adequate biocompatibility and body clearance. Herein, a series of FeII complexes bearing polypyridine […]

SCIENTIFIC PRESENTATIONS USING PHOTOSOUND PRODUCTS AT SPIE 2024

We look forward to seeing you at one of the scientific presentations using PhotoSound Technologies, Inc. products during SPIE Photonics West 2024. See the list of presentations below. 12842-15 The new development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy Author(s): Wei Zhang, Dale Litzenberg, […]

SPIE Photonics West 2024

PhotoSound Technologies is excited to attend this year’s SPIE Photonics West BiOS -the industry’s most important biophotonics, biomedical optics, and imaging meeting being held in San Francisco, CA January 27 – February 1, 2024.  Come talk to us and see our products in person at this year’s BIOS Exhibition at Photonics West in San Francisco on January […]

MONODISPERSE SUB-100 NM AU NANOSHELLS FOR LOW-FLUENCE DEEP-TISSUE PHOTOACOUSTIC IMAGING

August 4, 2023 Author(s): Luis D. B. Manuel, Vinion Devpaul Vincely, Carolyn Bayer, and Kevin M. McPeak ABSTRACT Nanoparticles with high absorption cross sections will advance therapeutic and bioimaging nanomedicine technologies. While Au nanoshells have shown great promise in nanomedicine, state-of-the-art synthesis methods result in scattering-dominant particles, mitigating their efficacy in absorption-based techniques that leverage […]

SIZE-TUNABLE ICG-BASED CONTRAST AGENT PLATFORM FOR TARGETED NEAR-INFRARED PHOTOACOUSTIC IMAGING

2022 Dec 11 Author(s): Shrishti Singh, Giovanni Giammanco, Chih-Hsiang Hu, Joshua Bush, Leandro Soto Cordova, Dylan J Lawrence, Jeffrey L Moran, Parag V Chitnis, Remi Veneziano ABSTRACT Near-infrared photoacoustic imaging (NIR-PAI) combines the advantages of optical and ultrasound imaging to provide anatomical and functional information of tissues with high resolution. Although NIR-PAI is promising, its widespread use is hindered by […]

FUNCTIONAL PHOTOACOUSTIC IMAGING FOR PLACENTAL MONITORING: A MINI REVIEW

available on 2024-09-29 Author(s): Vinoin Devpaul Vincely, Carolyn L Bayer ABSTRACT The placenta, a highly vascularized interface between the mother and fetus, undergoes dramatic anatomical and functional changes during pregnancy. These changes occur both during healthy development and adverse pathologies of pregnancy, such as preeclampsia. Abnormal placental development can lead to life-long health impacts on both the […]