Tag: Legion AMP

Clinical Pilot Study of Ionizing Radiation Acoustic Imaging for Real-Time Visualization of Radiation Therapy Dose Delivery in Cancer Patients

Author(s): K. C. Cuneo, W. Zhang, D. Litzenberg, Y. Huang, S. Hadley, I. Oraiqat, K.-W. Chang, G. Gonzalez, S. Dykstra, M. Zhang, E. G. Moros, P. L. Carson, I. El Naqa, and X. Wang ABSTRACT This study aimed to evaluate the feasibility of using ionizing radiation acoustic imaging (iRAI) to map the delivered dose in […]

On the importance of low-frequency signals in functional and molecular photoacoustic computed tomography

Author(s): Tri Vu, Paul Klippel, Aidan J. Canning, Chenshuo Ma, Huijuan Zhang, Ludmila A. Kasatkina, Yuqi Tang, Jun Xia, Vladislav V. Verkhusha, Tuan Vo-Dinh, Yun Jing, Junjie Yao ABSTRACT In photoacoustic computed tomography (PACT) with short-pulsed laser excitation, wideband acoustic signals are generated in biological tissues with frequencies related to the effective shapes and sizes […]

Machine-Learning-Based Colorectal Tissue Classification via Acoustic Resolution Photoacoustic Microscopy

Author(s): Shangqing Tong, Peng Ge, Yanan Jiao, Zhaofu Ma, Ziye Li, Longhai Liu, Feng Gao, Xiaohui Du, Fei Gao ABSTRACT Colorectal cancer is a deadly disease that has become increasingly prevalent in recent years. Early detection is crucial for saving lives, but traditional diagnostic methods such as colonoscopy and biopsy have limitations. Colonoscopy cannot provide detailed information within the tissues affected by cancer, […]

Assessment of a Single-Element Scanning System for Enhanced Photoacoustic Imaging of Brain Hemorrhage

Author(s): Juliana Benavides Lara, Ravi Prakash, Kamran Avanaki ABSTRACT The use of photoacoustic brain imaging for hemorrhage detection holds significant clinical importance. This study focuses on the performance of sensitivity and detection capabilities of a single-element scanning system, considering the remarkable signal-to-noise ratio of photoacoustic signals generated by a single-element transducer. By employing blood vessel-like phantoms and […]

Radiomics-driven perfusion prediction in clinical photoacoustic foot imaging

Author(s): Chuqin Huang a, Yanda Cheng a, Xiaoyu Zhang b, Ye Zhan c, Wenhan Zheng a, Isabel Komornicki d, Linda M. Harris d, Wenyao Xu b, Jun Xia a ABSTRACT Accurate assessment of tissue perfusion is essential for managing chronic foot ulcers in patients with diabetes and peripheral arterial disease. While photoacoustic (PA) imaging enables high-resolution […]

Enhanced clinical photoacoustic vascular imaging through a skin localization network and adaptive weighting

Author(s): Chuqin Huang, Emily Zheng, Wenhan Zheng, Huijuan Zhang, Yanda Cheng, Xiaoyu Zhang, Varun Shijo, Robert W. Bing, Isabel Komornicki, Linda M. Harris, Ermelinda Bonaccio, Kazuaki Takabe, Emma Zhang, Wenyao Xu, Jun Xia ABSTRACT Photoacoustic tomography (PAT) is an emerging imaging modality with widespread applications in both preclinical and clinical studies. Despite its promising capabilities to provide high-resolution images, the […]

Advancing precision photothermal therapy byintegrating armored gold nanostars with real-timephotoacoustic thermometry and imaging

Author(s): Aidan J. Canning, Tri Vu1, Luca Menozzi, Paul Klippel, Xinrong Chen, Jianing Chen,Theresa Charity, Khang Hoang, Joseph J. Yang, Yun Jing, Gregory M. Palmer5,Junjie Yao1, Tuan Vo-Dinh ABSTRACT Nanoparticle-mediated photothermal therapy (PTT) is a promising strategy for cancer treatment; however,nanoparticle instability and lack of precise imaging tools for real-time temperature monitoring during therapyand nanoparticle tracking […]

Ionizing radiation acoustic and ultrasound dual-modality imaging for visualization of dose on anatomical structures during radiotherapy

Author(s): Y. Huang, I. Oraiqat, D. Litzenberg, M. Subramanian Karthikesh, C. Tichacek, G. Gonzalez, Z. Xu, S. Dykstra, B. Li, S. Hadley, E. G. Moros, M. Zhang, P. L. Carson, K. C. Cuneo, X. Wang, I. El Naqa, and W. Zhang ABSTRACT The aim of this study is to visualize the radiation dose on anatomical structures during radiation […]

PHOTOSOUND TECHNOLOGIES, INC. ANNOUNCES PARNTERSHIP WITH VERASONICS

Partnership to Offer Vantage® Customers Expanded Capabilities in Applications Including Use with Photoacoustic Imaging, Thermoacoustic Imaging and Monitoring Radiation Therapy Houston, TX, June 24, 2025 – PhotoSound® Technologies, Inc., today announced a partnership with Verasonics, Inc. the leader in research ultrasound to offer customers the PhotoSound Legion™ AMP for use with Vantage® and Vantage NXT […]

The development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy

Author(s): Wei Zhang, Dale Litzenberg, Yaocai Huang, Kai-Wei Chang, Ibrahim Oraiqat, Scott Hadley, Eduardo G. Moros, Man Zhang, Paul L. Carson, Kyle C. Cuneo, Issam EI Naqa, Xueding Wang ABSTRACT Ionizing radiation acoustic imaging (iRAI) provides the potential to map the radiation dose during radiotherapy in real time. Described here is the development of iRAI volumetric imaging system in mapping the three-dimensional (3D) radiation dose deposition […]