Author(s): Tri Vu, Paul Klippel, Aidan J. Canning, Chenshuo Ma, Huijuan Zhang, Ludmila A. Kasatkina, Yuqi Tang, Jun Xia, Vladislav V. Verkhusha, Tuan Vo-Dinh, Yun Jing, Junjie Yao ABSTRACT In photoacoustic computed tomography (PACT) with short-pulsed laser excitation, wideband acoustic signals are generated in biological tissues with frequencies related to the effective shapes and sizes […]
Tag: photoacoustic computed tomography
Nanosecond Pulsed Light Emitting Diode (LED) Based High-Speed Photoacoustic Computed Tomography Using Multiple Single-Element Ultrasound Transducers
Author(s): Avishek Das, Manojit Pramanik ABSTRACT Light-emitting diodes (LEDs) emerge as a viable alternative to pulsed lasers in photoacoustic computed tomography (PACT) due to their low cost, compact form factor, wavelength flexibility, and reduced safety concerns. Unlike class-IV laser systems, LED-based excitation eliminates regulatory constraints while enabling high pulse-repetition rates (PRRs) and flexible modulation for […]
Single Wavelength Reconstruction of Optical Absorption Coefficient and Elastic Modulus Utilizing Photoacoustic Tomography
Author(s): L. Gong, C. Cai, F. Lin, Z. Xu, Z. Wang, H. Li, and Y. Liu ABSTRACT In this study, we utilized a home-made photoacoustic tomography system to recover optical absorption coefficient and elastic modulus under single wavelength. To reconstruct the optical absorption coefficient from photoacoustic measurements, we amalgamate the finite element solutions to the […]
3D Frequency-Domain Full Waveform Inversion for Whole-Breast Imaging With a Multi-Row Ring Array
Author(s): R. Ali, G. Jin, M. Singh, T. Mitcham, and N. Duric Comparison of 2D slicewise to 3D FWI with simulated multi-row ring array. Cylindrical wave transmits from a multi-row ring-array (32 rows; 256 elements per row; 22 cm diameter; 2.4 mm between rows) were simulated in three different numerical breast phantoms. Orthographic slice views […]
Utility of Low-Cost Multichannel Data Acquisition System for Photoacoustic Computed Tomography
Author(s): Zafar, Mohsin, Rayyan Manwar, Seyed Mohsen Ranjbaran, and Kamran Avanaki ABSTRACT Typically, multi-single-element photoacoustic computed tomography (PACT) systems utilize numerous ultrasound transducers arranged in cylindrical or hemispherical configurations for detection, combined with a single diffuse light source or multiple sparse light sources to illuminate the imaging target. While these systems produce high-quality 3D PA images, […]
Signal-domain speed-of-sound correction for ring-array-based photoacoustic tomography
Author(s): Daohuai Jiang, Hengrong Lan, Shangqing Tong, Xianzeng Zhang, Fei Gao ABSTRACT Photoacoustic imaging combines the advantages of optical and acoustic imaging, making it a promising tool in biomedical imaging. Photoacoustic tomography (PAT) reconstructs images by solving the inverse problem from detected photoacoustic waves to initial pressure map. The heterogeneous speed of sound (SoS) distribution in biological tissue significantly affects […]
Investigating the Impact of Chronical Prenatal Alcohol Exposure on Fetal Vascular Development Across Pregnancy Stages Using Photoacoustic Tomography
Author(s): Hao Yang, Md Farhan Tanvir, Huabei Jiang ABSTRACT This study investigates the effects of chronic prenatal alcohol exposure on fetal brain vascular development in mice using photoacoustic tomography. Key vascular parameters such as vessel diameter, density, and oxygen saturation were analyzed from embryonic Days 10 to 20. Results demonstrate significant vascular disruptions in alcohol-exposed groups […]
NON-INVASIVE 3D PHOTOACOUSTIC TOMOGRAPHY OF ANGIOGRAPHIC ANATOMY AND HEMODYNAMICS OF FATTY LIVERS IN RATS
Author(s): Xin Tong, Li Lin, Peng Hu, Rui Cao, Yang Zhang, Joshua Olick-Gibson,and Lihong V. Wang ABSTRACT Non-alcoholic fatty liver disease is the most common liver disorder worldwide, which strongly correlates to obesity, diabetes, and metabolic syndromes. Complementary to mainstream liver diagnostic modalities, photoacoustic tomography (PAT) can provide high-speed images with functional optical contrast. However, […]
