Author(s): N. Marshall, H.-P. Brecht, W. Thompson, D. Lawrence, V. Marshall, S. Toler, S. Emelianov, A. Yu, M. A. Anastasio, U. Villa, J. Maxwell, and S. Ermilov ABSTRACT We present the development of a photoacoustic tomography (PAT) imaging system with the demonstrated capability of obtaining high-throughput scans at a sustained rate of under 1 minute […]
Tag: Custom Systems & Algorithms
Machine-Learning-Based Colorectal Tissue Classification via Acoustic Resolution Photoacoustic Microscopy
Author(s): Shangqing Tong, Peng Ge, Yanan Jiao, Zhaofu Ma, Ziye Li, Longhai Liu, Feng Gao, Xiaohui Du, Fei Gao ABSTRACT Colorectal cancer is a deadly disease that has become increasingly prevalent in recent years. Early detection is crucial for saving lives, but traditional diagnostic methods such as colonoscopy and biopsy have limitations. Colonoscopy cannot provide detailed information within the tissues affected by cancer, […]
Nanosecond Pulsed Light Emitting Diode (LED) Based High-Speed Photoacoustic Computed Tomography Using Multiple Single-Element Ultrasound Transducers
Author(s): Avishek Das, Manojit Pramanik ABSTRACT Light-emitting diodes (LEDs) emerge as a viable alternative to pulsed lasers in photoacoustic computed tomography (PACT) due to their low cost, compact form factor, wavelength flexibility, and reduced safety concerns. Unlike class-IV laser systems, LED-based excitation eliminates regulatory constraints while enabling high pulse-repetition rates (PRRs) and flexible modulation for […]
Transcranial acoustoelectric imaging (tABI) of seizure activity in human head model with neuronavigation
Author(s): Nadia Abu Farha1, Parker Harris, Margaret Allard, Teodoro Trujillo, Stephen Cowen, Katalin Gothard4, Martin Weinand, Paul Larson, Ying-Hui Chou, Nan-Kuei Chen, Yeonjoon Cheong, Matthew O’Donnell6, Russell S Witte ABSTRACT Abstract not yet added. Read the full publication → Citation N. Abu Farha, P. Harris, M. Allard, T. Trujillo, S. Cowen, K. Gothard, M. Weinand, P. […]
Probing the photophysical properties of fluorescent proteins using photoacoustic pump-probe spectroscopy and imaging
Author(s): F. Ghane Golmohamadi, A. Mehmood, H. T. Phan, F.-J. Schmitt, and J. Laufer ABSTRACT Pump-probe excitation of fluorophores has been shown to overcome the limitations of conventional multiwavelength imaging and linear unmixing approaches by providing fluorophore-specific contrast whilst eliminating the dominant background signal of endogenous chromophores. In this study, methods for generating pump-probe signals and images are […]
Utility of Low-Cost Multichannel Data Acquisition System for Photoacoustic Computed Tomography
Author(s): Zafar, Mohsin, Rayyan Manwar, Seyed Mohsen Ranjbaran, and Kamran Avanaki ABSTRACT Typically, multi-single-element photoacoustic computed tomography (PACT) systems utilize numerous ultrasound transducers arranged in cylindrical or hemispherical configurations for detection, combined with a single diffuse light source or multiple sparse light sources to illuminate the imaging target. While these systems produce high-quality 3D PA images, […]
The development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy
Author(s): Wei Zhang, Dale Litzenberg, Yaocai Huang, Kai-Wei Chang, Ibrahim Oraiqat, Scott Hadley, Eduardo G. Moros, Man Zhang, Paul L. Carson, Kyle C. Cuneo, Issam EI Naqa, Xueding Wang ABSTRACT Ionizing radiation acoustic imaging (iRAI) provides the potential to map the radiation dose during radiotherapy in real time. Described here is the development of iRAI volumetric imaging system in mapping the three-dimensional (3D) radiation dose deposition […]
Spatiotemporal Image Reconstruction to Enable High-Frame-Rate Dynamic Photoacoustic Tomography with Rotating-Gantry Volumetric Imagers
Author(s): Refik Mert Cam, Chao Wang, Weylan Thompson, Sergey A. Ermilov, Mark A. Anastasio, Umberto Villa ABSTRACT Dynamic photoacoustic computed tomography (PACT) is a valuable imaging technique for monitoring physiological processes. However, current dynamic PACT imaging techniques are often limited to two-dimensional spatial imaging. Although volumetric PACT imagers are commercially available, these systems typically employ a rotating measurement gantry in […]
CHARACTERIZING A PHOTOACOUSTIC AND FLUORESCENCE IMAGING PLATFORM FOR PRECLINICAL MURINE LONGITUDINAL STUDIES
Author(s): Weylan R. Thompson, Hans-Peter F. Brecht, Vassili Ivanov, Anthony M. Yu, Diego S. Dumani, Dylan J. Lawrence, Stanislav Y. Emelianov, Sergey A. Ermilov PAT volumes and slices of in vivo mouse scans. The top PAT row shows 3D renders of the PAT volumes scanned at wavelengths (a) 532 nm for superficial structures, (b) 710 nm for deep structures with deoxygenated […]
