TriTomTM Contrast Agent Develpoment The development of novel optical imaging contrast agents requires extensive testing in both phantoms and animal models to ensure the safety and utility of the agent for in vivo applications. However, evaluating the biodistribution and clearance of a contrast agent remains challenging in preclinical studies due to limited whole-body real-time imaging […]
Tag: photoacoustic tomography
Anatomical Imaging Application Note
TriTom™ Photoacoustic Imaging Platform: Small Animal Anatomical Imaging The ability to directly visualize and evaluate anatomical structures and biological processes in small animal models at the whole-body level is critical for understanding the pathophysiology of human diseases. The TriTom™ small animal imaging platform provides noninvasive high-resolution photoacoustic tomography (PAT) images that can be used to extract functional and […]
Brain Imaging Application Note
Photoacoustic Neuroimaging with the TriTomTM Brain imaging, or neuroimaging, is used to understand the relationship between brain function and behavior and study the underlying causes of neurological and psychiatric diseases. It is important in helping to understand the relationship between specific areas of the brain and what function they serve. Photoacoustic Imaging (PAI) relies on differential […]
Cancer Imaging Application Note
Cancer Detection and Monitoring with the TriTomTM Photoacoustic imaging has become a popular tool in preclinical cancer research as a noninvasive technique for monitoring tumor growth and therapeutic response. Specifically, photoacoustic imaging can provide high-sensitivity images of both superficial and deep vasculature and quantitative assessment of blood oxygen saturation without exogenous contrast. The TriTom small […]
Spatiotemporal Image Reconstruction to Enable High-Frame-Rate Dynamic Photoacoustic Tomography with Rotating-Gantry Volumetric Imagers
Author(s): Refik Mert Cam, Chao Wang, Weylan Thompson, Sergey A. Ermilov, Mark A. Anastasio, Umberto Villa ABSTRACT Significance Dynamic photoacoustic computed tomography (PACT) is a valuable imaging technique for monitoring physiological processes. However, current dynamic PACT imaging techniques are often limited to two-dimensional spatial imaging. Although volumetric PACT imagers are commercially available, these systems typically employ a rotating measurement gantry […]
SPIE Photonics West 2024
PhotoSound Technologies is excited to attend this year’s SPIE Photonics West BiOS -the industry’s most important biophotonics, biomedical optics, and imaging meeting being held in San Francisco, CA January 27 – February 1, 2024. Come talk to us and see our products in person at this year’s BIOS Exhibition at Photonics West in San Francisco on January […]
SPHERICAL-VIEW PHOTOACOUSTIC TOMOGRAPHY FOR MONITORING IN VIVO PLACENTAL FUNCTION
29 September 2020 Author(s): Kristie Huda , Chengxi Wu , Jaclyn G. Sider, Carolyn L. Bayer ABSTRACT Photoacoustic tomography has great potential to image dynamic functional changes in vivo. Many tomographic systems are built with a circular view geometry, necessitating a linear translation along one axis of the subject to obtain a three-dimensional volume. In this work, we […]
NON-INVASIVE 3D PHOTOACOUSTIC TOMOGRAPHY OF ANGIOGRAPHIC ANATOMY AND HEMODYNAMICS OF FATTY LIVERS IN RATS
17 November 2022 Author(s): Xin Tong, Li Lin, Peng Hu, Rui Cao, Yang Zhang, Joshua Olick-Gibson,and Lihong V. Wang ABSTRACT Non-alcoholic fatty liver disease is the most common liver disorder worldwide, which strongly correlates to obesity, diabetes, and metabolic syndromes. Complementary to mainstream liver diagnostic modalities, photoacoustic tomography (PAT) can provide high-speed images with functional […]
WHOLE-BODY HUMAN UTLRASOUND TOMOGRAPHY
ABSTRACT We developed a system for whole-body human ultrasound tomography in reflection andtransmission modes. A custom 512-element ultrasound receiver array with a rotating single-element ultrasound transmitter are used to generate 2D isotropically resolved images across the entire human cross-section. We demonstrate this technique in regions such as the abdomen and legs in healthy volunteers. Compared […]
A COMBINED ULTRASOUND AND PHOTOACOUSTIC IMAGING PLATFORM FOR CLINICAL RESEARCH APPLICATIONS
3 March 2022 Author(s): Weylan Thompson, Hans-Peter Brecht, Sergey A. Ermilov, Vassili Ivanov ABSTRACT We present the continued development of a clinical ultrasound (US) imaging device with a photoacoustic (PA) mode. The combined USPA imaging platform is designed around a compact US component capable of B-mode, M-mode, color Doppler, and pulsed wave Doppler US imaging modes with a […]