Tag: preclinical research
TriTom Whole-Body 3D Image of a Mouse
Multimodal Imaging
What is Multimodal Imaging? Multimodal Imaging is the combination of two or more imaging modalities that leverage the strengths of each modality. Multimodal imaging enhances the anatomical, functional, and molecular information obtained in a single imaging session. PhotoSound’s Tritom imaging system utilizes the same short pulse duration OPO light source to generate the photoacoustic as […]
Tissue Engineering & Regeneration
What is Tissue Engineering & Regeneration? Tissue engineering is the process of creating new tissues and organs to replace damaged or diseased tissues. Photoacoustic tomography can be used to evaluate tissue regeneration and vascularization. PhotoSound Product Used TriTom Photoacoustic Image-Guided Delivery of Plasmonic-Nanoparticle-Labeled Mesenchymal Stem Cells to the Spinal Cord MoleculUS A Combined Ultrasound and […]
Disease Monitoring
PhotoSounds OEM Line of products is an ideal starting point for the development of custom systems where the parallel acquisition of multiple channels is required. All our ADCs are streaming and allow the continuous acquisition of data straight to the receiving computer for processing or storage. PhotoSound’s ADCs are feature-rich, they have multiple electronic and […]
Anatomical Imaging
What is anatomical imaging? Anatomical imaging is used to visualize the structure and organization of tissues and organs within the body. Photoacoustic tomography generates high-resolution images of blood-rich tissues without the need for exogenous contrast agents. PhotoSound Product Used TriTom Dual-Scan Photoacoustic Tomography for the Imaging of Vascular Structure on Foot Photoacoustic tomography to assess […]
Therapeutic Monitoring
PhotoSounds OEM Line of products is an ideal starting point for the development of custom systems where the parallel acquisition of multiple channels is required. All our ADCs are streaming and allow the continuous acquisition of data straight to the receiving computer for processing or storage. PhotoSound’s ADCs are feature-rich, they have multiple electronic and […]
Molecular Imaging
What is Molecular Imaging? Molecular imaging enables the visualization, characterization, and quantification of biological processes that take place at the cellular and subcellular levels. PhotoSound Product Used TriTom Commercial Small Animal Imaging Could Aid Disease Detection Indocyanine green dye based bimodal contrast agent tested by photoacoustic/fluorescence tomography setup A preclinical small animal imaging platform combining […]
COMMERCIAL SMALL ANIMAL IMAGING COULD AID DISEASE DETECTION
Authors: Mark Little ABSTRACT The development of anticancer metastatic therapies for human clinical trials requires meticulous evaluation of efficacy and optimization of small animal test models in preclinical experimentation. Critical information on morphology and the molecular microenvironment of tumors is currently obtained and monitored using noninvasive, in vivo imaging methods. Detection of individual, small tumors […]
A PRECLINICAL SMALL ANIMAL IMAGING PLATFORM COMBINING MULTI-ANGLE PHOTOACOUSTIC AND FLUORESCENCE PROJECTIONS INTO CO-REGISTERED 3D MAPS
Authors: Weylan Thompson1, Anthony Yu2,3, Diego S. Dumani2,3,4, Jason Cook5, Mark A. Anastasio6, Stanislav Y. Emelianov2,3, Sergey A. Ermilov1 ABSTRACT We present the results on development of the 3D imaging platform combining photoacoustic tomography and fluorescence (PAFT) for preclinical and biological research. This combined multimodal imaging instrument addresses known deficiencies in sensitivity, spatial resolution, and […]