Authors: Diego S. Dumani1,2, Anthony Yu1,2, Weylan Thompson3, Hans-Peter Brecht3, Vassili Ivanov3, Mark A. Anastasio4, Jason Cook5, Sergey A. Ermilov3, Stanislav Y. Emelianov1,2 ABSTRACT We report on the development of a preclinical 3D imaging platform integrating photoacoustic tomography and fluorescence (PAFT). The proposed multimodal imaging concept addresses known deficiencies in sensitivity, anatomical registration, and spatial […]
Tag: preclinical research
NON-INVASIVE PHOTOACOUSTIC COMPUTED TOMOGRAPHY OF RAT HEART ANATOMY AND FUNCTION
Author(s): Xin Tong, Li Lin, Peng Hu, Rui Cao, Yang Zhang, Joshua Olick-Gibson, Lihong V. Wang ABSTRACT Non-alcoholic fatty liver disease is the most common liver disorder worldwide, which strongly correlates to obesity, diabetes, and metabolic syndromes. Complementary to mainstream liver diagnostic modalities, photoacoustic tomography (PAT) can provide high-speed images with functional optical contrast. However, PAT has not been demonstrated to […]
HIGH-SPEED THREE-DIMENSIONAL PHOTOACOUSTIC COMPUTED TOMOGRAPHY FOR PRECLINICAL RESEARCH AND CLINICAL TRANSLATION
Authors: Li Lin1,4, Peng Hu1,4, Xin Tong1,4, Rui Cao1, Xiaoyun Yuan1,2, David C. Garrett1, Junhui Shi1,3, Konstantin Maslov1 & Lihong V. Wang1 ABSTRACT Photoacoustic computed tomography (PACT) has generated increasing interest for uses in preclinical research and clinical translation. However, the imaging depth, speed, and quality of existing PACT systems have previously limited the potential applications […]