Author(s): M. Pérez-Liva, M. Alonso de Leciñana, M. Gutiérrez-Fernández, J. Camacho Sosa Dias, J. F. Cruza, J. Rodríguez-Pardo, I. García-Suárez, F. Laso-García, J. L. Herraiz, and L. Elvira Segura ABSTRACT Photoacoustic (PA) imaging, by integrating optical and ultrasound (US) modalities, combines high spatial resolution with deep tissue penetration, making it a transformative tool in biomedical […]
Tag: preclinical research
Contrast Agent Development Application Note
TriTomTM Contrast Agent Develpoment The development of novel optical imaging contrast agents requires extensive testing in both phantoms and animal models to ensure the safety and utility of the agent for in vivo applications. However, evaluating the biodistribution and clearance of a contrast agent remains challenging in preclinical studies due to limited whole-body real-time imaging […]
Anatomical Imaging Application Note
TriTom™ Photoacoustic Imaging Platform: Small Animal Anatomical Imaging The ability to directly visualize and evaluate anatomical structures and biological processes in small animal models at the whole-body level is critical for understanding the pathophysiology of human diseases. The TriTom™ small animal imaging platform provides noninvasive high-resolution photoacoustic tomography (PAT) images that can be used to extract functional and […]
Brain Imaging Application Note
Photoacoustic Neuroimaging with the TriTomTM Brain imaging, or neuroimaging, is used to understand the relationship between brain function and behavior and study the underlying causes of neurological and psychiatric diseases. It is important in helping to understand the relationship between specific areas of the brain and what function they serve. Photoacoustic Imaging (PAI) relies on differential […]
Cancer Imaging Application Note
Cancer Detection and Monitoring with the TriTomTM Photoacoustic imaging has become a popular tool in preclinical cancer research as a noninvasive technique for monitoring tumor growth and therapeutic response. Specifically, photoacoustic imaging can provide high-sensitivity images of both superficial and deep vasculature and quantitative assessment of blood oxygen saturation without exogenous contrast. The TriTom small […]
Spatiotemporal Image Reconstruction to Enable High-Frame-Rate Dynamic Photoacoustic Tomography with Rotating-Gantry Volumetric Imagers
Author(s): Refik Mert Cam, Chao Wang, Weylan Thompson, Sergey A. Ermilov, Mark A. Anastasio, Umberto Villa ABSTRACT Dynamic photoacoustic computed tomography (PACT) is a valuable imaging technique for monitoring physiological processes. However, current dynamic PACT imaging techniques are often limited to two-dimensional spatial imaging. Although volumetric PACT imagers are commercially available, these systems typically employ a rotating measurement gantry in […]
Arizona State University Uses the TriTom
SIZE-TUNABLE ICG-BASED CONTRAST AGENT PLATFORM FOR TARGETED NEAR-INFRARED PHOTOACOUSTIC IMAGING
Author(s): Shrishti Singh, Giovanni Giammanco, Chih-Hsiang Hu, Joshua Bush, Leandro Soto Cordova, Dylan J Lawrence, Jeffrey L Moran, Parag V Chitnis, Remi Veneziano Fig. 6. In vivo imaging using RGD-JAAZ particles. (A) Schematic and photograph of the 3D PAI acquisition on the TriTom™ imaging system. (B) Coronal and axial slabs of the baseline PA signal acquired at 895 nm. (C) Representative coronal and […]
FUNCTIONAL PHOTOACOUSTIC IMAGING FOR PLACENTAL MONITORING: A MINI REVIEW
Author(s): Vinoin Devpaul Vincely, Carolyn L Bayer ABSTRACT The placenta, a highly vascularized interface between the mother and fetus, undergoes dramatic anatomical and functional changes during pregnancy. These changes occur both during healthy development and adverse pathologies of pregnancy, such as preeclampsia. Abnormal placental development can lead to life-long health impacts on both the mother and […]
NON-INVASIVE 3D PHOTOACOUSTIC TOMOGRAPHY OF ANGIOGRAPHIC ANATOMY AND HEMODYNAMICS OF FATTY LIVERS IN RATS
Author(s): Xin Tong, Li Lin, Peng Hu, Rui Cao, Yang Zhang, Joshua Olick-Gibson,and Lihong V. Wang ABSTRACT Non-alcoholic fatty liver disease is the most common liver disorder worldwide, which strongly correlates to obesity, diabetes, and metabolic syndromes. Complementary to mainstream liver diagnostic modalities, photoacoustic tomography (PAT) can provide high-speed images with functional optical contrast. However, […]
