Tag: TriTom

CO-REGISTERED PHOTOACOUSTIC AND FLUORESCENT IMAGING OF A SWITCHABLE NANOPROBE BASED ON J-AGGREGATES OF INDOCYANINE GREEN

Authors: Diego S. Dumani, Hans-Peter Brecht, Vassili Ivanov, Ryan Deschner, Justin T. Harris, Kimberly A. Homan, Jason R. Cook, Stanislav Y. Emelianov, Sergey A. Ermilov ABSTRACT We introduce a preclinical imaging platform – a 3D photoacoustic/fluorescence tomography (PAFT) instrument augmented with an environmentally responsive dual-contrast biocompatible nanoprobe. The PAFT instrument was designed for simultaneous acquisition […]

A PRECLINICAL SMALL ANIMAL IMAGING PLATFORM COMBINING MULTI-ANGLE PHOTOACOUSTIC AND FLUORESCENCE PROJECTIONS INTO CO-REGISTERED 3D MAPS

Authors: Weylan Thompson, Anthony Yu, Diego S. Dumani, Jason Cook, Mark A. Anastasio, Stanislav Y. Emelianov, Sergey A. Ermilov ABSTRACT We present the results on development of the 3D imaging platform combining photoacoustic tomography and fluorescence (PAFT) for preclinical and biological research. This combined multimodal imaging instrument addresses known deficiencies in sensitivity, spatial resolution, and […]