Author(s): L. Mikhailova, E. Vysotina, M. Timofeeva, E. Kopoleva, V. Gulinyan, O. Pashina, K. Arabuli, O. Gusliakova, E. Prikhozhdenko, X. Qi, A. Petrov, E. Ageev, M. Petrov, C. De Angelis, M. Durymanov, G. Sukhorukov, and M. V. Zyuzin ABSTRACT Melanoma, a highly malignant and complex form of cancer, has increased in global incidence, with a […]
Tag: TriTom
TriTom System Featured on Lithuanian National TV
We’re proud to share that PhotoSound Technologies’ TriTom™ system was recently featured on Lithuanian national television. The broadcast segment highlighted innovations in medical imaging, beginning with our laser partner EKSPLA (14:20), followed by the TriTom system (14:55), and continuing with other leaders in photoacoustic imaging, including PA Imaging (19:15) and iThera Medical (21:30). Watch the […]
Contrast Agent Development Application Note
TriTomTM Contrast Agent Develpoment The development of novel optical imaging contrast agents requires extensive testing in both phantoms and animal models to ensure the safety and utility of the agent for in vivo applications. However, evaluating the biodistribution and clearance of a contrast agent remains challenging in preclinical studies due to limited whole-body real-time imaging […]
Anatomical Imaging Application Note
TriTom™ Photoacoustic Imaging Platform: Small Animal Anatomical Imaging The ability to directly visualize and evaluate anatomical structures and biological processes in small animal models at the whole-body level is critical for understanding the pathophysiology of human diseases. The TriTom™ small animal imaging platform provides noninvasive high-resolution photoacoustic tomography (PAT) images that can be used to extract functional and […]
Brain Imaging Application Note
Photoacoustic Neuroimaging with the TriTomTM Brain imaging, or neuroimaging, is used to understand the relationship between brain function and behavior and study the underlying causes of neurological and psychiatric diseases. It is important in helping to understand the relationship between specific areas of the brain and what function they serve. Photoacoustic Imaging (PAI) relies on differential […]
Cancer Imaging Application Note
Cancer Detection and Monitoring with the TriTomTM Photoacoustic imaging has become a popular tool in preclinical cancer research as a noninvasive technique for monitoring tumor growth and therapeutic response. Specifically, photoacoustic imaging can provide high-sensitivity images of both superficial and deep vasculature and quantitative assessment of blood oxygen saturation without exogenous contrast. The TriTom small […]
Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy
Author(s): Iaroslav B. Belyaev, Ivan V. Zelepukin, Polina A. Kotelnikova, Gleb V. Tikhonowski, Anton A. Popov, Alina Yu. Kapitannikova, Jugal Barman, Alexey N. Kopylov, Daniil N. Bratashov, Ekaterina S. Prikhozhdenko, Andrei V. Kabashin, Sergey M. Deyev, Andrei V. Zvyagin ABSTRACT Biodegradable nanomaterials can significantly improve the safety profile of nanomedicine. Germanium nanoparticles (Ge NPs) with a safe biodegradation pathway are developed as efficient photothermal converters for biomedical […]
GPU-Accelerated 3D Volumetric X-Ray-Induced Acoustic Computed Tomography
Author(s): Donghyun Lee, Eun-Yeong Park, Seongwook Choi, Hyeongsub Kim, Jung-joon Min, Changho Lee, and Chulhong Kim ABSTRACT X-ray acoustic imaging is a hybrid biomedical imaging technique that can acoustically monitor X-ray absorption distribution in biological tissues through the X-ray induced acoustic effect. In this study, we developed a 3D volumetric X-ray-induced acoustic computed tomography (XACT) […]
Spatiotemporal Image Reconstruction to Enable High-Frame-Rate Dynamic Photoacoustic Tomography with Rotating-Gantry Volumetric Imagers
Author(s): Refik Mert Cam, Chao Wang, Weylan Thompson, Sergey A. Ermilov, Mark A. Anastasio, Umberto Villa ABSTRACT Dynamic photoacoustic computed tomography (PACT) is a valuable imaging technique for monitoring physiological processes. However, current dynamic PACT imaging techniques are often limited to two-dimensional spatial imaging. Although volumetric PACT imagers are commercially available, these systems typically employ a rotating measurement gantry in […]
Water-Soluble Fe(II) Complexes for Theranostic Application: Synthesis, Photoacoustic Imaging, and Photothermal Conversion
Authors: Maeva Delcroix, Dr. Anil Reddy Marri, Stéphane Parant, Dr. Philippe C. Gros, Dr. Mathilde Bouché ABSTRACT Significant effort focused on developing photoactivatable theranostics for localized image guided therapy of cancer by thermal ablation. In this context iron complexes were recently identified as photoactivatable theranostic agents with adequate biocompatibility and body clearance. Herein, a series of FeII complexes bearing polypyridine […]
