Author(s): Lidia Mikhailova, Elizaveta Vysotina, Maria Timofeeva, Elena Kopoleva, Van Gulinyan, Olesia Pashina, Konstantin Arabuli, Olga Gusliakova, Ekaterina Prikhozhdenko, Xiaoli Qi, Andrey Petrov, Eduard Ageev, Mihail Petrov, Constantino De Angelis, Mikhail Durymanov, Gleb Sukhorukov, Mikhail V. ZyuzinLidia Mikhailova, Elizaveta Vysotina, Maria Timofeeva, Elena Kopoleva, Van Gulinyan, Olesia Pashina, Konstantin Arabuli, Olga Gusliakova, Ekaterina Prikhozhdenko, Xiaoli Qi, […]
Category: Publication
Rotational ultrasound and photoacoustic tomography of the human body
Author(s): Yang Zhang, Shuai Na, Jonathan J. Russin, Karteekeya Sastry, Li Lin, Junfu Zheng, Yilin Luo, Xin Tong, Yujin An, Peng Hu, Konstantin Maslov, Tze-Woei Tan, Charles Y. Liu, Lihong V. Wang ABSTRACT Imaging the human body’s morphological and angiographic information is essential for diagnosing, monitoring, and treating medical conditions. Ultrasonography performs the morphological assessment of […]
3D protoacoustic radiography: A proof of principle study
Author(s): Prabodh K Pandey, Gilberto Gonzalez, Kristina Bjegovic, Leshan Sun, Yong Chen, Liangzhong Xiang ABSTRACT We propose protoacoustic radiography (PAR), an imaging modality combining proton excitation and acoustic detection for three-dimensional (3D) imaging from a single proton projection. PAR avoids the effect of multiple Coulomb scattering in imaging by detecting ultrasound. Proton-induced acoustic waves propagate spherically, […]
Ionizing radiation acoustic and ultrasound dual-modality imaging for visualization of dose on anatomical structures during radiotherapy
Author(s): Yaocai Huang, Ibrahim Oraiqat, Dale Litzenberg, Madhumithra Subramanian Karthikes, Christopher Tichacek, Glebys Gonzalez, Zhanpeng Xu, Sarah Dykstra, Borui Li, Scott Hadley, Eduardo G. Moros, Man Zhang, Paul L. Carson, Kyle C. Cuneo, Xueding Wang, Issam El Naqa, Wei Zhang ABSTRACT The aim of this study is to visualize the radiation dose on anatomical structures during radiation therapy (RT) by […]
4D IN VIVO DOSIMETRY FOR A FLASH ELECTRON BEAM USING RADIATION-INDUCED ACOUSTIC IMAGING
Authors: Kristina Bjegovic, Leshan Sun, Prabodh Pandey, Veljko Grilj, Paola Ballesteros-Zebadua, Ryan Paisley, Gilberto Gonzalez, Siqi Wang, Marie Catherine Vozenin, Charles L Limoli and Shawn (Liangzhong) Xiang ABSTRACT Objective. The primary goal of this research is to demonstrate the feasibility of radiation-induced acoustic imaging (RAI) as a volumetric dosimetry tool for ultra-high dose rate FLASH […]
TOWARD REAL-TIME, VOLUMETRIC DOSIMETRY FOR FLASH-CAPABLE CLINICAL SYNCHROCYCLOTRONS USING PROTOACOUSTIC IMAGING
Authors: Siqi Wang, Gilberto Gonzalez, Daniel Rocky Owen, Leshan Sun, Yan Liu, Townsend Zwart, Yong Chen, Liangzhong Xiang ABSTRACT BackgroundRadiation delivery with ultra-high dose rate (FLASH) radiotherapy (RT) holds promise for improving treatment outcomes and reducing side effects but poses challenges in radiation delivery accuracy due to its ultra-high dose rates. This necessitates the development […]
REAL-TIME TRACKING OF THE BRAGG PEAK DURING PROTON THERAPY VIA 3D PROTOACOUSTIC IMAGING IN A CLINICAL SCENARIO
Authors: Siqi Wang, Gilberto Gonzalez, Leshan Sun, Yifei Xu, Prabodh Pandey, Yong Chen & Shawn (Liangzhong) Xiang ABSTRACT Proton radiotherapy favored over X-ray photon therapy due to its reduced radiation exposure to surrounding healthy tissues, is highly dependent on the accurate positioning of the Bragg peak. Existing methods like PET and prompt gamma imaging to […]
Multifunctional PtCuTe Nanosheets with Strong ROS Scavenging and ROS-Independent Antibacterial Properties Promote Diabetic Wound Healing
Author(s): Yaru Guo, Shuai Ding, Changshuai Shang, Chenguang Zhang, Menggang Li, Qinghua Zhang, Lin Gu, Boon Chin Heng, Shihan Zhang, Feng Mei, Ying Huang, Xuehui Zhang, Mingming Xu, Jiuhui Jiang, Shaojun Guo, Xuliang Deng, Lili Chen Abstract Nanozymes, as one of the most efficient reactive oxygen species (ROS)-scavenging biomaterials, are receiving wide attention in promoting diabetic wound healing. Despite recent attempts at improving the catalytic efficiency of Pt-based nanozymes (e.g., PtCu, […]
Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy
Author(s): Iaroslav B. Belyaev, Ivan V. Zelepukin, Polina A. Kotelnikova, Gleb V. Tikhonowski, Anton A. Popov, Alina Yu. Kapitannikova, Jugal Barman, Alexey N. Kopylov, Daniil N. Bratashov, Ekaterina S. Prikhozhdenko, Andrei V. Kabashin, Sergey M. Deyev, Andrei V. Zvyagin Abstract Biodegradable nanomaterials can significantly improve the safety profile of nanomedicine. Germanium nanoparticles (Ge NPs) with a safe biodegradation pathway are developed as efficient photothermal converters for biomedical […]
The development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy
Author(s): Wei Zhang, Dale Litzenberg, Yaocai Huang, Kai-Wei Chang, Ibrahim Oraiqat, Scott Hadley, Eduardo G. Moros, Man Zhang, Paul L. Carson, Kyle C. Cuneo, Issam EI Naqa, Xueding Wang Abstract Ionizing radiation acoustic imaging (iRAI) provides the potential to map the radiation dose during radiotherapy in real time. Described here is the development of iRAI volumetric imaging system in mapping the three-dimensional (3D) radiation dose deposition […]