Authors: Seongwook Choi,1; Sinyoung Park,1; Ayoung Pyo,2; Dong-Yeon Kim,3 ; Jung-Joon Min,4 ; Changho Lee,4,5,6; Chulhong Kim,1,7 ABSTRACT X-ray-induced acoustic computed tomography (XACT) has shown great potential as a hybrid imaging modality for real-time non-invasive x-ray dosimetry and low-dose three- dimensional (3D) imaging. While promising, one drawback of the XACT system is the underlying low signal-to-noise ratio […]
Category: Publication
SIZE-ADJUSTABLE RING-SHAPE PHOTOACOUSTIC TOMOGRAPHY IMAGER IN VIVO
Author(s): Daohuai Jiang1,2,3, Yifei Xu1, Hengrong Lan1,2,3, Yuting Shen1, Yifan Zhang1,Feng Gao1, Li Liu4*, Fei Gao1,5* ABSTRACT Photoacoustic tomography (PAT) has become a novel biomedical imaging modality for scientific research and clinical diagnosis. It combines the advantages of spectroscopic optical absorption contrast and acoustic resolution with deep penetration. In this article, an imaging size-adjustable PAT […]
NON-INVASIVE PHOTOACOUSTIC COMPUTED TOMOGRAPHY OF RAT HEART ANATOMY AND FUNCTION
Author(s): Xin Tong, Li Lin, Peng Hu, Rui Cao, Yang Zhang, Joshua Olick-Gibson, Lihong V. Wang ABSTRACT Non-alcoholic fatty liver disease is the most common liver disorder worldwide, which strongly correlates to obesity, diabetes, and metabolic syndromes. Complementary to mainstream liver diagnostic modalities, photoacoustic tomography (PAT) can provide high-speed images with functional optical contrast. However, PAT has not been demonstrated to […]
REAL-TIME, VOLUMETRIC IMAGING OF RADIATION DOSE DELIVERY DEEP INTO THE LIVER DURING CANCER TREATMENT
Authors: Wei Zhang, Ibrahim Oraiqat, Dale Litzenberg, Kai-Wei Chang, Scott Hadley, Noora Ba Sunbul, Martha M. Matuszak, Christopher J. Tichacek, Eduardo G. Moros, Paul L. Carson, Kyle C. Cuneo, Xueding Wang, & Issam El Naqa ABSTRACT Ionizing radiation acoustic imaging (iRAI) allows online monitoring of radiation’s interactions with tissues during radiation therapy, providing real-time, adaptive […]
MONITORING NEONATAL BRAIN HEMORRHAGE PROGRESSION BY PHOTOACOUSTIC TOMOGRAPHY
Author(s): Tianqi Shan, Hao Yang, Shixie Jiang, and Huabei Jiang ABSTRACT Neonatal brain hemorrhage (NBH) is the most common neurological disorder in neonates and its clinical interventions are very limited. Understanding the pathology of NBH by non-invasive in-vivo characterization of standardized animal models is essential for developing potential treatments. Currently, there is no suitable tool […]
CHARACTERIZING A PHOTOACOUSTIC AND FLUORESCENCE IMAGING PLATFORM FOR PRECLINICAL MURINE LONGITUDINAL STUDIES
Author(s): Weylan R. Thompson, Hans-Peter F. Brecht, Vassili Ivanov, Anthony M. Yu, Diego S. Dumani, Dylan J. Lawrence, Stanislav Y. Emelianov, Sergey A. Ermilov ABSTRACT SIGNIFICANCE To effectively study preclinical animal models, medical imaging technology must be developed with a high enough resolution and sensitivity to perform anatomical, functional, and molecular assessments. Photoacoustic (PA) tomography […]
BIODEGRADABLE AND BIOCOMPATIBLE SEMICONDUCTOR NANOCRYSTALS AS NIR-II PHOTOACOUSTIC IMAGING CONTRAST AGENTS
Author(s): Vinoin Devpaul Vincely, Swathi P. Katakam, Kristie Huda, Xingjian Zhong, Joshua C. Kays, Allison M. Dennis, Carolyn L. Bayer ABSTRACT Transabdominal imaging using photoacoustics (PA) is limited by optical attenuation of tissue due to high scattering and absorption in the near infrared (NIR) window. Tissue attenuation is lowered when imaging with longer wavelengths in the NIR window (> 950 nm). […]
IMPROVING PHOTOACOUSTIC IMAGING IN LOW SIGNAL-TO-NOISE RATIO BY USING SPATIAL AND POLARITY COHERENCE
Author(s): Qiuqin Mao, Weiwei Zhao, Xiaoqin Qian, Chao Tao, Xiaojun Liu ABSTRACT To suppress the noise and sidelobe of photoacoustic images, a method is proposed combined with spatial coherence and polarity coherence. In this method, PA signals are delayed, multiplied, then performed polarity coherence, and finally summed. The polarity of delayed-and-multiplied signals rather than the amplitude is considered in polarity coherence operation. The polarity coherence […]
DEEP LEARNING ENABLED REAL-TIME PHOTOACOUSTIC TOMOGRAPHY SYSTEM VIA SINGLE DATA ACQUISITION CHANNEL
Author(s): Hengrong Lan, Daohuai Jiang, Feng Gao, Fei Gao ABSTRACT Photoacoustic computed tomography (PACT) combines the optical contrast of optical imaging and the penetrability of sonography. In this work, we develop a novel PACT system to provide real-time imaging, which is achieved by a 120-elements ultrasound array only using a single data acquisition (DAQ) channel. To reduce the channel number of DAQ, we superimpose 30 nearby […]
Y-NET: HYBRID DEEP LEARNING IMAGE RECONSTRUCTION FOR PHOTOACOUSTIC TOMOGRAPHY IN VIVO
Author(s): Hengrong Lan, Daohuai Jiang, Changchun Yang, Feng Gao, Fei Gao ABSTRACT Conventional reconstruction algorithms (e.g., delay-and-sum) used in photoacoustic imaging (PAI) provide a fast solution while many artifacts remain, especially for limited-view with ill-posed problem. In this paper, we propose a new convolutional neural network (CNN) framework Y-Net: a CNN architecture to reconstruct the initial PA pressure distribution by optimizing both raw data and beamformed images […]