Author(s): Farzin Ghane Golmohamadi, Amna Mehmood, Hoang Trong Phan, Franz-Josef Schmitt, Jan Laufer ABSTRACT Pump-probe excitation of fluorophores has been shown to overcome the limitations of conventional multiwavelength imaging and linear unmixing approaches by providing fluorophore-specific contrast whilst eliminating the dominant background signal of endogenous chromophores. In this study, methods for generating pump-probe signals and images are investigated that […]
Tag: molecular imaging
A 3D IMAGING SYSTEM INTEGRATING PHOTOACOUSTIC AND FLUORESCENCE ORTHOGONAL PROJECTIONS FOR ANATOMICAL, FUNCTIONAL, AND MOLECULAR ASSESSMENT OF RODENT MODELS
16 March 2018 Authors: Hans P. Brecht, Vassili Ivanov, Diego S. Dumani, Stanislav Y. Emelianov, Mark A. Anastasio, Sergey A. Ermilov ABSTRACT We have developed a preclinical 3D imaging instrument integrating photoacoustic tomography and fluorescence (PAFT) addressing known deficiencies in sensitivity and spatial resolution of the individual imaging components. PAFT is designed for simultaneous acquisition of photoacoustic and fluorescence orthogonal […]
Molecular Imaging
What is Molecular Imaging? Molecular imaging enables the visualization, characterization, and quantification of biological processes that take place at the cellular and subcellular levels. PhotoSound Product Used TriTom Commercial Small Animal Imaging Could Aid Disease Detection Indocyanine green dye based bimodal contrast agent tested by photoacoustic/fluorescence tomography setup A preclinical small animal imaging platform combining […]