Tag: cancer

Targeted contrast agents and activatable probes for photoacoustic imaging of cancer

Author(s): Zhenxiang Zhao, Chelsea Swartchick, Jefferson Chan ABSTRACT Photoacoustic (PA) imaging has emerged as a powerful technique for the high resolution visualization of biological processes within deep tissue. Through the development and application of exogenous targeted contrast agents and activatable probes that can respond to a given cancer biomarker, researchers can image molecular events in vivo during cancer progression. […]

Clinical Pilot Study of Ionizing Radiation Acoustic Imaging for Real-Time Visualization of Radiation Therapy Dose Delivery in Cancer Patients

Author(s): K. C. Cuneo, W. Zhang, D. Litzenberg, Y. Huang, S. Hadley, I. Oraiqat, K.-W. Chang, G. Gonzalez, S. Dykstra, M. Zhang, E. G. Moros, P. L. Carson, I. El Naqa, and X. Wang ABSTRACT This study aimed to evaluate the feasibility of using ionizing radiation acoustic imaging (iRAI) to map the delivered dose in […]

TriTom System Featured on Lithuanian National TV

We’re proud to share that PhotoSound Technologies’ TriTom™ system was recently featured on Lithuanian national television. The broadcast segment highlighted innovations in medical imaging, beginning with our laser partner EKSPLA (14:20), followed by the TriTom system (14:55), and continuing with other leaders in photoacoustic imaging, including PA Imaging (19:15) and iThera Medical (21:30). Watch the […]

Cancer Imaging Application Note

Cancer Detection and Monitoring with the TriTomTM Photoacoustic imaging has become a popular tool in preclinical cancer research as a noninvasive technique for monitoring tumor growth and therapeutic response. Specifically, photoacoustic imaging can provide high-sensitivity images of both superficial and deep vasculature and quantitative assessment of blood oxygen saturation without exogenous contrast. The TriTom small […]

Laser-Synthesized Germanium Nanoparticles as Biodegradable Material for Near-Infrared Photoacoustic Imaging and Cancer Phototherapy

Author(s): Iaroslav B. Belyaev, Ivan V. Zelepukin, Polina A. Kotelnikova, Gleb V. Tikhonowski, Anton A. Popov, Alina Yu. Kapitannikova, Jugal Barman, Alexey N. Kopylov, Daniil N. Bratashov, Ekaterina S. Prikhozhdenko, Andrei V. Kabashin, Sergey M. Deyev, Andrei V. Zvyagin ABSTRACT Biodegradable nanomaterials can significantly improve the safety profile of nanomedicine. Germanium nanoparticles (Ge NPs) with a safe biodegradation pathway are developed as efficient photothermal converters for biomedical […]

The development of ionizing radiation acoustic imaging (iRAI) for mapping the dose deep in the patient body during radiation therapy

Author(s): Wei Zhang, Dale Litzenberg, Yaocai Huang, Kai-Wei Chang, Ibrahim Oraiqat, Scott Hadley, Eduardo G. Moros, Man Zhang, Paul L. Carson, Kyle C. Cuneo, Issam EI Naqa, Xueding Wang ABSTRACT Ionizing radiation acoustic imaging (iRAI) provides the potential to map the radiation dose during radiotherapy in real time. Described here is the development of iRAI volumetric imaging system in mapping the three-dimensional (3D) radiation dose deposition […]

Discrete Wavelet Transformation for the Sensitive Detection of Ultrashort Radiation Pulse with Radiation-Induced Acoustics

Authors: Rick Van Bergen, Leshan Sun, Prabodh Kumar Pandey, Siqi Wang, Kristina Bjegovic, Gilberto Gonzalez, Yong Chen, Richard Lopata, Liangzhong Xiang ABSTRACT Radiation-induced acoustics (RIA) shows promise in advancing radiological imaging and radiotherapy dosimetry methods. However, RIA signals often require extensive averaging to achieve reasonable signal-to-noise ratios, which increases patient radiation exposure and limits real-time […]